Hot Products
Hot products from BioCrick which is a professional high-purity natural products manufacturer are well known to scientists around the world because of their high purity and stability. Each product is a chemical compound or substance produced by a living organism—that is, found in nature. In the broadest sense, natural products include any substance produced by life.Natural products remain the best sources of drugs and drug leads, and this remains true today despite the fact that many pharmaceutical companies have deemphasized natural products research in favor of HTP screening of combinatorial libraries during the past 2 decades. From 1940s to date, 131 (74.8%) out of 175 small molecule anticancer drugs are natural product-based/inspired, with 85 (48.6%) being either natural products or derived therefrom. From 1981 to date, 79 (80%) out of 99 small molecule anticancer drugs are natural product-based/inspired, with 53 (53%) being either natural products or derived therefrom. Among the 20 approved small molecule New Chemical Entities (NCEs) in 2010, a half of them are natural products.
Hot products from the professional high-purity natural products manufacturer
| Cat.No. | Product Name |
|---|---|
| BCN7436 | Eriobofuran |
| 1. Eriobofuran, a phytoalexin, has antimicrobialactivity, it can inhibit strongly the spore germination and germ tube growth of Pestalotia funerea, a host-pathogenic fungus of loquat tree. | |
| BCN7437 | Nudiposide |
| 1. Nudiposide has significant neuroprotective activities against glutamate-injured neurotoxicity in HT22 cells. 2. Nudiposide exhibits protective effect against sepsis in a mouse model and can decrease the plasma levels of TNF-α, IL-10 and ALT activity. | |
| BCN7438 | Arborinine |
| 1. Arborinin shows cytotoxicity against nine drug sensitive and multidrug-resistant cancer cell lines, it also can strongly induce apoptosis in CCRF-CEM cells and cell cycle arrest in the G0/G1 and S phases. 2. Arborinine possesses moderate levels of anti-hepatitis C virus(HCV) activities with the IC₅₀ values being 6.4 ± 0.7 ug/ml. 3. Arborinine shows mild in vitro antibacterial activity. 4. Arborinine shows antifeedant activity against Spodoptera frugiperda. | |
| BCN7441 | Canophyllal |
| 1. Canophyllal shows antiplasmodial activity against the W2 strain of Plasmodium falciparum which is resistant to chloroquine and other antimalarial drugs. | |
| BCN7443 | Questinol |
| 1. Questinol exhibits significant anti-obesity activity. 2. Questinol shows anti-inflammatory effect in lipopolysaccharide (LPS)-stimulated RAW 264.7 cells, it can inhibit the production of pro-inflammatory cytokines, including TNF-α, IL-1β, and IL-6 and inhibit NO and PGE2 production. | |
| BCN7446 | Questin |
| 1. Questin has promising inhibitory potential against AChE, BChE, and BACE1, it may be used in the development of therapeutic or preventive agents for Alzheimer's disease. 2. Questin is toxic to the human A549 lung cell line. 3. Questin is a Cdc25B phosphatase inhibitor, it inhibited the enzymatic activity of Cdc25B phosphatase with the IC(50) value of 34 microg/mL, it also strongly inhibited the growth of human colon cancer cells, SW620 with the GI(50) value of 0.9 microg/mL. 4. Questin shows considerably high immunosuppressive activity. | |
| BCN7447 | Prehelminthosporol |
| 1. Prehelminthosporol is a phytotoxin, it may play an important role in pathogenesis by killing or weakening plant cells in advance of the growing hyphae and facilitating nutrient uptake and further growth of the fungus in plant tissue. | |
| BCN7449 | Neuchromenin |
| 1. (-)-Neuchromenin is an inducer of neurite outgrowth of PC12 cells at concentration of 2.5-10 ug/ml. | |
