Hot Products
Hot products from BioCrick which is a professional high-purity natural products manufacturer are well known to scientists around the world because of their high purity and stability. Each product is a chemical compound or substance produced by a living organism—that is, found in nature. In the broadest sense, natural products include any substance produced by life.Natural products remain the best sources of drugs and drug leads, and this remains true today despite the fact that many pharmaceutical companies have deemphasized natural products research in favor of HTP screening of combinatorial libraries during the past 2 decades. From 1940s to date, 131 (74.8%) out of 175 small molecule anticancer drugs are natural product-based/inspired, with 85 (48.6%) being either natural products or derived therefrom. From 1981 to date, 79 (80%) out of 99 small molecule anticancer drugs are natural product-based/inspired, with 53 (53%) being either natural products or derived therefrom. Among the 20 approved small molecule New Chemical Entities (NCEs) in 2010, a half of them are natural products.
Hot products from the professional high-purity natural products manufacturer
| Cat.No. | Product Name |
|---|---|
| BCN7500 | 16-Hydroxycleroda-3,13-dien-15,16-olide |
| 1. 16-Hydroxycleroda-3,13-dien-15,16-olide, and prodigiosin are presented as candidates for autophagy inducers that can trigger cell death in a supplement or alternative medicine for cancer therapy. 2. 16-Hydroxycleroda-3,13-dien-15,16-olide has anti-inflammatory activity, it shows promising NO inhibitory activity at 10 ug/mL. 3. 16-Hydroxycleroda-3,13-dien-15,16-olide regulates the expression of histone-modifying enzymes PRC2 complex and induces apoptosis in CML K562 cells. | |
| BCN7501 | 7-Hydroxycadalene |
| 1. 7-Hydroxycadalene shows cytotoxicity activity against HCT-15 cell line with IC50 18.89 ± 1.2 uM. | |
| BCN7506 | Dehydroperilloxin |
| 1. Dehydroperilloxin possesses inhibitory activity against cyclooxygenase-1, with the IC(50) value of 30.4 microM. | |
| BCN7507 | Germanicol |
| 1. Germanicol induces selective growth inhibitory effects in human colon HCT-116 and HT29 cancer cells through induction of apoptosis, cell cycle arrest and inhibition of cell migration. 2. Germanicol may have anti-inflammatory effects . | |
| BCN7509 | Rutamarin |
| 1. Rutamarin exhibits remarkable cytotoxic activity against HT29 cells (IC50 value of 5.6 uM), it has the potential to be developed as an anticancer agent. 2. (+)-Rutamarin is effective in inhibiting EBV DNA replication and virion production but shows little adverse effect on cell proliferation. 3. (+)-Rutamarin is a dual inducer of both GLUT4 translocation and expression efficiently ameliorates glucose homeostasis in insulin-resistant mice. | |
| BCN7513 | 8-Hydroxy-ar-turmerone |
| 1. 8-Hydroxy-ar-turmerone may exhibit antitumor activity against breast cancer cells via cell death and cell cycle arrest. | |
| BCN7515 | 4-Methoxycinnamyl alcohol |
| 1. 4-Methoxycinnamyl alcohol shows toxicity against MCF-7, HeLa and DU145 cancer cell line. | |
| BCN7516 | ar-Turmerone |
| 1. ar-Turmerone could be used as a low cost botanical insecticide for integrated management of cabbage looper in vegetable production. 2. ar-Turmerone may have notable antibacterial activity to Bacillus cereus and Staphylococcus aureus, antifungal activity to Aspergillus niger, and cytotoxic activity to Hs 578T (breast tumor) and PC-3 (prostate tumor) cells. 3. ar-Turmerone shows larvicidal and biting deterrent activity against Aedes aegypti and Anopheles quadrimaculatus (Culicidae: Diptera). 4. ar-Turmerone exerts potent anti-inflammatory effects via suppression of the inflammatory cytokines IFN-γ and IL-2. 5. ar-Turmerone induces neural stem cells (NSCs) proliferation, hence it constitutes a promising candidate to support regeneration in neurologic disease. 6. ar-Turmerone displays anticonvulsant properties in both acute seizure models in mice and modulates the expression patterns of two seizure-related genes (c-fos and brain-derived neurotrophic factor [bdnf]) in zebrafish. 7. ar-Turmerone has a cytotoxic effect on L-1210 and HL-60 cells, it also has a repressive effect on P388D1 lymphocytic leukemia. | |
