Hot Products
Hot products from BioCrick which is a professional high-purity natural products manufacturer are well known to scientists around the world because of their high purity and stability. Each product is a chemical compound or substance produced by a living organism—that is, found in nature. In the broadest sense, natural products include any substance produced by life.Natural products remain the best sources of drugs and drug leads, and this remains true today despite the fact that many pharmaceutical companies have deemphasized natural products research in favor of HTP screening of combinatorial libraries during the past 2 decades. From 1940s to date, 131 (74.8%) out of 175 small molecule anticancer drugs are natural product-based/inspired, with 85 (48.6%) being either natural products or derived therefrom. From 1981 to date, 79 (80%) out of 99 small molecule anticancer drugs are natural product-based/inspired, with 53 (53%) being either natural products or derived therefrom. Among the 20 approved small molecule New Chemical Entities (NCEs) in 2010, a half of them are natural products.
Hot products from the professional high-purity natural products manufacturer
| Cat.No. | Product Name |
|---|---|
| BCN7518 | Gentisin |
| 1. Gentisin is a novel inhibitor of vascular smooth muscle cells (VSMC) proliferation with an IC50 value of 7.84 uM. 2. Gentisin has mutagenic activity. | |
| BCN7521 | Anhydrosecoisolariciresinol |
| 1. Anhydrosecoisolariciresinol can significantly decrease the growth of human breast cancer MCF-7 and MDA-MB-231 cell lines at 50 and 100 microM. | |
| BCN6442 | Goshonoside F5 |
| 1. Goshonoside F5 has anti-inflammatory activity, it significantly inhibits the pro-inflammatory response induced by LPS, both in vitro and in vivo. | |
| BCN7523 | 1,7-Dihydroxy-2,3-dimethoxyxanthone |
| 1. 1,7-Dihydroxy-2,3-dimethoxyxanthone shows significant inhibitory effects on LPS-induced NO production in BV2 microglia cells. 2. 1,7-Dihydroxy-2,3-dimethoxyxanthone antagonises in a non competitive but, reversible manner the contractions induced by chemical inflammatory mediators in the guinea pig trachea in vitro, thus, it may have medicinal use in the management of inflammation, asthma and allergy. | |
| BCN7524 | 1-Hydroxyacridone |
| 1. 1-Hydroxyacridone has potential antiviral activity. | |
| BCN7526 | Neogrifolin |
| 1. Neogrifolin is a potential candidate for osteosarcoma, it can induce concentration- and time-dependent suppression of proliferation and induce apoptosis in U2OS and MG63 osteosarcoma cell lines. 2. Neogrifolin possesses antimicrobial activities against Bacillus cereus and Enterococcus faecalis, the MIC values of 20 and 0.5 microg/mL, respectively. 3. Neogrifolin exhibits inhibitory activity against nitric oxide (NO) production stimulated by lipopolysaccharide (LPS) in RAW 264.7 cells with the IC50value of 23.3 microM. | |
| BCN7527 | Luvangetin |
| 1. Luvangetin can inhibit NO and PGE2 production in LPS-stimulated BV2 cells, it may have anti-inflammatory activity. 2. Luvangetin shows significant protection against pylorus-ligated and aspirin-induced gastric ulcers in rats and cold restraint stress-induced gastric ulcers in rats and guinea pigs. | |
| BCN7871 | Rubioncolin C |
| 1. Rubioncolin C shows good cytotoxicity with IC50 value of 1.53 uM and NF-κB inhibitory activity with IC50 value of 2.97 uM. | |
