Hot Products
Hot products from BioCrick which is a professional high-purity natural products manufacturer are well known to scientists around the world because of their high purity and stability. Each product is a chemical compound or substance produced by a living organism—that is, found in nature. In the broadest sense, natural products include any substance produced by life.Natural products remain the best sources of drugs and drug leads, and this remains true today despite the fact that many pharmaceutical companies have deemphasized natural products research in favor of HTP screening of combinatorial libraries during the past 2 decades. From 1940s to date, 131 (74.8%) out of 175 small molecule anticancer drugs are natural product-based/inspired, with 85 (48.6%) being either natural products or derived therefrom. From 1981 to date, 79 (80%) out of 99 small molecule anticancer drugs are natural product-based/inspired, with 53 (53%) being either natural products or derived therefrom. Among the 20 approved small molecule New Chemical Entities (NCEs) in 2010, a half of them are natural products.
Hot products from the professional high-purity natural products manufacturer
| Cat.No. | Product Name |
|---|---|
| BCN7394 | Hispidanin B |
| 1. Hispidanin B shows significant cytotoxicities against tumor cell lines SGC7901, SMMC7721, and K562, with IC50 values of 10.7, 9.8, and 13.7 uM, respectively. | |
| BCN7400 | Chlojaponilactone B |
| 1. Chlojaponilactone B has anti-inflammatory activity, it exhibits pronounced inhibition of nitric oxide (NO) production in lipopolysaccharide (LPS)-induced RAW 264.7 macrophages. | |
| BCN7404 | Hispanone |
| 1. Hispanone possesses anti-inflammatory activity, it shows inhibition of superoxide anion generation and elastase release. | |
| BCN7406 | 2alpha,19alpha-Dihydroxy-3-oxo-urs-12-en-28-oic acid |
| 1. 2alpha,19alpha-Dihydroxy-3-oxo-urs-12-en-28-oic acid has anti-HIV activity. 2. 2alpha,19alpha-Dihydroxy-3-oxo-urs-12-en-28-oic acid shows an inhibitory effect on the activation of Epstein-Barr virus early antigen (EBV-EA) induced by 12-O-tetradecanoylphorbol-13-acetate (TPA) and causes a significant delay of two-stage carcinogenesis on mouse skin. | |
| BCN7407 | 2-Hydroxy-3-methoxybenzoic acid glucose ester |
| 1. 2-Hydroxy-3-methoxybenzoic acid glucose ester shows a potent antagonistic activity against platelet activating factor (PAF), it can prevent the mice from the PAF-induced death at a dose of 300 micrograms/mouse. | |
| BCN7408 | Ditryptophenaline |
| 1. Ditryptophenaline inhibits substance P receptor for potential analgesic and anti-inflammatory activity. | |
| BCN7410 | Aflavarin |
| 1. Aflavarin exhibits potent antifeedant activity against the fungivorous beetle Carpophilus hemipterus. | |
| BCN7414 | Aflatrem |
| 1. Aflatrem is a tremorgenic mycotoxin with acute neurotoxic effects, a single low dose of aflatrem is able to induce degeneration of neuronal processes in hippocampal neurotransmitter systems. 2. Aflatrem potentiates the gamma-aminobutyric acid (GABA)-induced chloride current, the potentiating action of aflatrem on the GABAA receptor channel may explain the initial symptoms of intoxication caused by aflatrem in vivo. | |
