Hot Natural Products & Bioactive Compounds

BioCrick offers high-purity natural products and bioactive compounds for scientific research. Our natural product collection includes compounds derived from plants, microorganisms and other biological sources and is widely used in pharmacological, biochemical and drug discovery research.

Natural products remain an important source of bioactive molecules and drug leads. BioCrick provides researchers with high-quality natural product compounds together with catalog numbers, product information and biological activity data.

Hot Products from BioCrick

Showing 273 - 280 of 9359 hot products

BioCrick hot natural products and bioactive compounds
Catalog No. Product Name
BCC1957 Sobetirome
Thyromimetic; high affinity agonist at thyroid hormone receptor (TR) <span class='symbol'>&#946;</span> and TR<span class='symbol'>&#945;</span> receptors (K<sub>D</sub> values are 67 and 440 pM respectively). Displays 5- and 100-fold greater potency than the endogenous agonist T<sub>3</sub> <em>in vitro</em> at TR<span class='symbol'>&#945;</span><sub>1</sub> and TR<span class='symbol'>&#946;</span><sub>1</sub> receptors respectively. Promotes reverse cholesterol transport in chow- and fat-fed mice. Induces proliferation of hepatocytes and pancreatic acinar cells in rats independent of prior tissue injury.
BCC1963 SR1078
Agonist of retinoic acid receptor-related orphan receptors (ROR) ROR<span class='symbol'>&#945;</span>/<span class='symbol'>&#947;</span>. Increases transcription of ROR<span class='symbol'>&#945;</span> target genes; thought to increase p53 stability.
BCC1965 SRT3109
SRT3109 is a CXCR2 ligand for use in the treatment of chemokine mediated diseases and conditions.
BCC1966 SRT3190
SRT3190 is CXCR2 ligand.
BCC1970 SU 5402
Potent and selective vascular endothelial growth factor receptor (VEGFR) and fibroblast growth factor receptor (FGFR) inhibitor (IC<sub>50</sub> values are 0.02, 0.03, 0.51 and &gt; 100 <span class='symbol'>&#956;</span>M at VEGFR2, FGFR1, PDGFR<span class='symbol'>&#946;</span> and EGFR respectively). Inhibits embryonic left-right determination and exhibits potent anticancer activity <em>in vitro</em> and <em>in vivo</em>. Also attenuates integrin <span class='symbol'>&#946;</span>4-induced differentiation of neural stem cells.
BCC1974 SU5416
Inhibitor of vascular endothelial growth factor receptor (VEGFR) that also inhibits other tyrosine kinases KIT, MET, FLT3 and RET. Displays no activity against EGFR, HER2, IGF1R and PDGFR. Inhibits tumor vascularization and growth of multiple tumor types.
BCC1975 Tacalcitol
Synthetic vitamin D<sub>3</sub> analog. Promotes normal bone development by regulating calcium. Modulates immunological and inflammatory processes; induces nerve growth factor production in epidermal keratinocytes.
BCC1981 Talnetant
Potent and selective non-peptide NK<sub>3</sub> receptor antagonist (K<sub>i</sub> values are 1, 144 and &#062;100000 nM for human NK<sub>3</sub>, NK<sub>2</sub> and NK<sub>1</sub> receptors respectively). Selective over a panel of &#062;60 receptors, enzymes and ion channels at concentrations of 1 or 10 <span class='symbol'>&#956;</span>M. Inhibits NKB-induced Ca<sup>2+</sup> mobilization <em>in vitro</em> (IC<sub>50</sub> = 16.6 nM) and inhibits NK<sub>3</sub>-agonist-induced behavioral responses <em>in vivo</em>. Orally active and brain penetrant.