Hot Products

Hot products from BioCrick which is a professional high-purity natural products manufacturer are well known to scientists around the world because of their high purity and stability. Each product is a chemical compound or substance produced by a living organism—that is, found in nature. In the broadest sense, natural products include any substance produced by life.Natural products remain the best sources of drugs and drug leads, and this remains true today despite the fact that many pharmaceutical companies have deemphasized natural products research in favor of HTP screening of combinatorial libraries during the past 2 decades. From 1940s to date, 131 (74.8%) out of 175 small molecule anticancer drugs are natural product-based/inspired, with 85 (48.6%) being either natural products or derived therefrom. From 1981 to date, 79 (80%) out of 99 small molecule anticancer drugs are natural product-based/inspired, with 53 (53%) being either natural products or derived therefrom. Among the 20 approved small molecule New Chemical Entities (NCEs) in 2010, a half of them are natural products.

Hot products from the professional high-purity natural products manufacturer

Cat.No. Product Name
BCN7462 Glycoborinine
1. Glycoborinine is a potential molecule against cancer cells, it can induce HepG2 apoptosis through the mitochondrial-dependent pathway. 2. Glycoborinine has photo-activated antimicrobial activity, it shows moderate inhibition on Nde I, Xba I, Nco I and Bcl I.
BCN7463 Conodurine
1. Conodurine shows inhibition activity for acetyl (AChE) and butyrylcholinesterase (BuChE). 2. Conodurine shows leishmanicidal and antibacterial activities.
BCN7468 Jasminin
1. Jasminin is a bitter compound.
BCN7471 3'-O-Methylmurraol
1. 3'-O-Methylmurraol exhibits inhibition (IC50 ≤ 7.31 ug/mL) of superoxide anion generation by human neutrophils in response to formyl-l-methionyl-l-leucyl-l-phenylalanine/cytochalasin B (fMLP/CB), it may have potential anti-inflammatory activity .
BCN7472 Kimcuongin
1. Kimcuongin shows vasorelaxing activity with IC50 values of 37.7 uM.
BCN7475 Morolic acid
1. Morolic acid and moronic acid have shown sustained antidiabetic and antihyperglycemic action possibly mediated by an insulin sensitization with consequent changes of glucose, cholesterol and triglycerides, in part mediated by inhibition of 11β-HSD 1. 2. Morolic acid exhibits pronounced radical scavenging activity against the stable 2,2-diphenyl-1-picrylhydrazyl radical and is a potent inhibitor of neutrophil elastase and cyclooxygenase-1 and -2 in vitro. 3. Morolic acid shows effectiveness on the mouse ear inflammation induced by repeated applications of 12-O-tetradecanoylphorbol 13-acetate and on the phospholipase A2-induced foot paw edema. 4. Morolic acid can inhibit leukotriene B4 production in rat polymorphonuclear leukocytes stimulated with calcium ionophore A 23187. 5. Morolic acid exhibits promising anti-HIV activity, it also exhibits moderate inhibitory activity against glycogen phosphorylase.
BCN7476 2-Acetoxy-3-deacetoxycaesaldekarin E
1. 2-Acetoxy-3-deacetoxycaesaldekarin E shows significant dose-dependent inhibitory effects on Plasmodium falciparum FCR-3/A2 growth in vitro.
BCN7477 Neotripterifordin
1. Neotripterifordin shows potent anti-HIV replication activity in H9 lymphocyte cells with an EC50 of 25 nM and TI of 125.