Hot Products
Hot products from BioCrick which is a professional high-purity natural products manufacturer are well known to scientists around the world because of their high purity and stability. Each product is a chemical compound or substance produced by a living organism—that is, found in nature. In the broadest sense, natural products include any substance produced by life.Natural products remain the best sources of drugs and drug leads, and this remains true today despite the fact that many pharmaceutical companies have deemphasized natural products research in favor of HTP screening of combinatorial libraries during the past 2 decades. From 1940s to date, 131 (74.8%) out of 175 small molecule anticancer drugs are natural product-based/inspired, with 85 (48.6%) being either natural products or derived therefrom. From 1981 to date, 79 (80%) out of 99 small molecule anticancer drugs are natural product-based/inspired, with 53 (53%) being either natural products or derived therefrom. Among the 20 approved small molecule New Chemical Entities (NCEs) in 2010, a half of them are natural products.
Hot products from the professional high-purity natural products manufacturer
Cat.No. | Product Name |
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BCN6447 | Piptocarphin F |
1. Piptocarphin F shows strong cytotoxic activities against mouse lymphoid tumor cell line P388. 2. Piptocarphin F shows cytotoxic activity (IC50 3.87–12.5 umol·L−1) against the human leukemic cell line HL-60. | |
BCN7422 | Altechromone A |
1. Altechromone A has antimicrobial activity, it is active against Bacillus subtilis, Escherichia coli, Pseudomonas fluorescens and Candida albicans with the MICs of 3.9, 3.9, 1.8, and 3.9 ug/ml, respectively. | |
BCN7423 | 1,5-Dihydroxyxanthone |
1. 1,5-Dihydroxyxanthone may have anticholinesterase activity on acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) enzymes. 2. 1,5-Dihydroxyxanthone exhibits the epidermal growth factor receptor (EGFR) -tyrosine kinase inhibitory activity, with the IC50 value of 90.34 nM. | |
BCN7424 | Bellidifolin |
1. Bellidifolin has anti-oxidation, anti-inflammatory and antitumor actions. 2. Bellidifolin may contribute to the protective effects associated with nerve injury initiated by hypoxia by mechanisms related to inhibition of cell apoptosis independent of the ERK pathway. 3. Bellidifolin exhibits hepatoprotective activities in vitro and in vivo. 4. Bellidifolin shows an antifungal effect (MIC values of 50 microg/mL). 5. Bellidifolin could be useful for treating type-2 diabetes, likely via the improvement of insulin resistance (IR). 6. Bellidifolin shows interesting inhibitory activity of monoamine oxidases (MAO) A. | |
BCN7425 | GB 2a |
1. GB 2a shows antioxidant activity. 2. GB 2a biflavonoid can promote inhibition on tyrosinase activity and reduced melanin biosynthesis in B16F10 cells, which suggests great potential for medical and cosmetic uses as a depigmenting agent. 3. GB 2a has anti-inflammatory effects, it can prevent the carrageenan-induced paw oedema. | |
BCN7426 | Isocudraniaxanthone A |
1. Isocudraniaxanthone A may have antimalarial activity. | |
BCN7433 | Diepiserratenediol |
1. Diepiserratenediol has potential activity to inhibit tumor promotion, it shows potent inhibitory effects on EBV-EA induction (100% inhibition at 1000 mol ratio/TPA). | |
BCN6395 | Arjunglucoside II |
1. Arjunglucoside II exhibits a moderate free radical scavenging activity. |