Hot Products
Hot products from BioCrick which is a professional high-purity natural products manufacturer are well known to scientists around the world because of their high purity and stability. Each product is a chemical compound or substance produced by a living organism—that is, found in nature. In the broadest sense, natural products include any substance produced by life.Natural products remain the best sources of drugs and drug leads, and this remains true today despite the fact that many pharmaceutical companies have deemphasized natural products research in favor of HTP screening of combinatorial libraries during the past 2 decades. From 1940s to date, 131 (74.8%) out of 175 small molecule anticancer drugs are natural product-based/inspired, with 85 (48.6%) being either natural products or derived therefrom. From 1981 to date, 79 (80%) out of 99 small molecule anticancer drugs are natural product-based/inspired, with 53 (53%) being either natural products or derived therefrom. Among the 20 approved small molecule New Chemical Entities (NCEs) in 2010, a half of them are natural products.
Hot products from the professional high-purity natural products manufacturer
| Cat.No. | Product Name |
|---|---|
| BCN8170 | Physcion 1-glucoside |
| 1. Physcion 8-O-beta-D-monoglucoside has anti-inflammatory activity, it can inhibit TNF-α-induced cytotoxicity and apoptosis in L929 cells via TNF-R1. | |
| BCN8125 | Hesperidin methylchalcone |
| 1. Hesperidin methylchalcone has anti-inflammatory effects, it can suppresse experimental gout arthritis in mice by inhibiting NF-κB activation. 2. Hesperidin methylchalcone is a promising new therapeutic approach to protecting the skin from the deleterious effects of UVB irradiation. 3. Hesperidin methylchalcone can regulate the expression of adhesion molecules in tumor necrosis factor-alpha-stimulated human umbilical vein endothelial cells. 4. Hesperidin methylchalcone has a protective effect against leakage of FITC-dextran in the cheek pouch after administration of various permeability-increasing substances. | |
| BCN8133 | Cytisine Hydrochloride |
| 1. Cytisine hydrochloride has toxicity. | |
| BCN8184 | Pulsatilla camphor |
| 1. Pulsatilla saponin D exhibits anticancer activities in various cancer types, it Inhibits autophagic flux and synergistically enhances the anticancer activity of chemotherapeutic agents against HeLa cells. 2. Pulsatilla saponin D has strong haemolytic activity. | |
| BCN8130 | Kaempferol-4'-O-beta-D-glucopyranoside |
| 1. Antihypertensive agent. | |
| BCN8158 | Ganoderiol A |
| 1. Ganoderiol A suppresses migration and adhesion of MDA-MB-231 cells by inhibiting FAK-SRC-Paxillin cascade pathway. | |
| BCN8128 | Pungiolide A |
| 1. Pungiolide A exhibits moderate cytotoxicities with IC50 values in the range of 0.90-6.84 uM. | |
| BCN8127 | Escin IIB |
| 1. Escin IIB has positive effects on acute inflammation in animals, it can inhibit the induced by serotonin in rats, the hind paw edema induced by carrageenin, and the scratching behavior induced by compound 48/80 in mice. 2. Escin IIB enhances Mg(2+) absorption from the digestive tract in mice, in which the constitutive, but not the inducible, NO synthase plays an important role. 3. Escin IIB shows gastroprotection on ethanol-induced gastric mucosal lesions, whereas endogenous prostaglandins, NO, capsaicin-sensitive afferent neurons, and the sympathetic nervous system participate. | |
