Hot Natural Products & Bioactive Compounds
BioCrick offers high-purity natural products and bioactive compounds for scientific research. Our natural product collection includes compounds derived from plants, microorganisms and other biological sources and is widely used in pharmacological, biochemical and drug discovery research.
Natural products remain an important source of bioactive molecules and drug leads. BioCrick provides researchers with high-quality natural product compounds together with catalog numbers, product information and biological activity data.
Hot Products from BioCrick
Showing 201 - 208 of 9359 hot products
| Catalog No. | Product Name |
|---|---|
| BCC1616 | H-1152 dihydrochloride |
|
Rho-kinase (ROCK) inhibitor that displays high selectivity over other protein kinases (IC<sub>50</sub> values are 0.012, 0.180, 0.360, 0.745, 3.03, 5.68 and 28.3 <span class='symbol'>μ</span>M for ROCKII, CAMKII, PKG, Aurora A, PKA, PKC and MLCK respectively). Inhibits sulprostone-induced contractions in guinea pig aorta (IC<sub>50</sub> = 190 nM) and displays proerectile effects in rats. Glycyl derivative available.
|
|
| BCC1619 | HIV-1 integrase inhibitor 2 |
|
HIV-1 integrase inhibitor 2 is an inhibitor of HIV-1 integrase used in the treatment of human immunodeficiency virus (HIV) infection
|
|
| BCC1623 | Hoechst 33258 |
|
Fluorescent dye. Binds the minor groove of DNA at A and T rich regions. Can be used as indicator of apoptosis.
|
|
| BCC1629 | Hoechst 33342 |
|
Cell permeable fluorescent DNA stain; binds minor groove of AT-rich regions. Used to quantify DNA in viable cells.
|
|
| BCC1636 | Hydroxyfasudil hydrochloride |
|
Cell-permeable active metabolite of Fasudil. Produces ATP-competitive and reversible inhibition of Rho-kinase and is ~ 100-fold selective over a range of other protein kinases. Inhibits neutrophil migration and produces potent vasodilatory effects <em>in vivo</em>.
|
|
| BCC1638 | Ibutamoren Mesylate |
|
High affinity ghrelin receptor agonist (pK<sub>i</sub> = 8.14). Growth hormone (GH) secretagog; stimulates GH release from rat pituitary cells <em>in vitro</em> (EC<sub>50</sub> = 1.3 nM) and enhances GH plasma levels <em>in vivo</em>. Also attenuates isoproterenol -induced lipolysis in rat adipocytes <em>in vitro</em>. Orally bioavailable.
|
|
| BCC1643 | IKK-3 Inhibitor |
|
Potent and selective IKKε inhibitor (pIC50 = 7.4). Exhibits >100-fold selectivity for IKKε over IKKα IKKβ, and a range of other kinases.
|
|
| BCC1646 | INCB 3284 dimesylate |
|
Potent, selective hCCR2 antagonist. Exhibits potent antagonism against monocyte chemoattractant molecule binding to hCCR2 and chemotaxis activity (IC<sub>50</sub> values are 3.7 and 4.7 nM respectively). Also displays weak hERG activity; inhibits the hERG potassium current (IC<sub>50</sub> = 84<span class='symbol'>μ</span>M). Orally bioavailable.
|
|