Hot Products
Hot products from BioCrick which is a professional high-purity natural products manufacturer are well known to scientists around the world because of their high purity and stability. Each product is a chemical compound or substance produced by a living organism—that is, found in nature. In the broadest sense, natural products include any substance produced by life.Natural products remain the best sources of drugs and drug leads, and this remains true today despite the fact that many pharmaceutical companies have deemphasized natural products research in favor of HTP screening of combinatorial libraries during the past 2 decades. From 1940s to date, 131 (74.8%) out of 175 small molecule anticancer drugs are natural product-based/inspired, with 85 (48.6%) being either natural products or derived therefrom. From 1981 to date, 79 (80%) out of 99 small molecule anticancer drugs are natural product-based/inspired, with 53 (53%) being either natural products or derived therefrom. Among the 20 approved small molecule New Chemical Entities (NCEs) in 2010, a half of them are natural products.
Hot products from the professional high-purity natural products manufacturer
| Cat.No. | Product Name |
|---|---|
| BCN2067 | Clivorine |
| 1. Clivorine has anti-proliferative function in L-02 cells may be due to its inducing cell apoptosis with independent of p53 protein. 2. Clivorine itself has direct toxicity on HEK293 cells, and phosphorylated JNK may play some role in counteracting the toxicity of Clivorine on HEK293 cells. 3. Clivorine induces hepatotoxicity and acute liver injury, which can be protected by quercetin, trolox and epidermal growth factor via inhibiting apoptotic cell death and ameliorating oxidative stress injury. | |
| BCN2074 | Crosemperine |
| 1. Crosemperine has antitumor and antimicrobial activity. | |
| BCN2076 | Crotalarine |
| 1. Crotalarine may possess antimicrobial, anti-inflammatory and antinociceptive activities. | |
| BCN2080 | Emiline |
| 1. (±)-Emiline displays good neuroprotective effect against the corticosterone-induced apoptosis in PC12 cells. | |
| BCN2082 | Fulvine |
| 1. Fulvine is a hepatotoxic pyrrolizidine alkaloid. 2. An aqueous solution of Fulvine can produce an acute pancreatopathy with interstitial oedema and secondary hypoxic dystrophy of the acinar cells, when administered at doses of 10 and 20 mg/kg body weight. | |
| BCN2087 | Jacobine |
| 1. Jacobine induces significant dose-dependent DNA-DNA interstrand cross-linking over the entire range of doses. 2. Jacobine, was catalyzed by guinea pig hepatic glutathione-S-transferase enzymes in in vitro experiments. | |
| BCN2088 | Jacoline |
| 1. Jacoline, jaconine, jacobine, and jacozine, the hepatotoxic alkaloids, are potentially carcinogenic, mutagenic, and teratogenic and may pose health hazards to the human consumer. 2. Jacoline, jacobine and jaconine show toxic side-effects. | |
| BCN2089 | Jaconine |
| 1. Jaconine, jacoline,jacobine, and jacozine, the hepatotoxic alkaloids, are potentially carcinogenic, mutagenic, and teratogenic and may pose health hazards to the human consumer. 2. Jaconine, jacobine and jacoline show toxic side-effects. | |
