Hot Natural Products & Bioactive Compounds
BioCrick offers high-purity natural products and bioactive compounds for scientific research. Our natural product collection includes compounds derived from plants, microorganisms and other biological sources and is widely used in pharmacological, biochemical and drug discovery research.
Natural products remain an important source of bioactive molecules and drug leads. BioCrick provides researchers with high-quality natural product compounds together with catalog numbers, product information and biological activity data.
Hot Products from BioCrick
Showing 105 - 112 of 9359 hot products
| Catalog No. | Product Name |
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| BCC1217 | Leupeptin, Microbial |
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Reversible inhibitor of trypsin-like and cysteine proteases such as calpain. Shown to inhibit activation-induced programmed cell death.
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| BCC1218 | Pepstatin A |
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Irreversible inhibitor of aspartic proteases. Inhibits lysosomal proteases and interferes with autolysosomal digestion when used in combination with E 64d.
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| BCC1219 | AEBSF.HCl |
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Broad spectrum, irreversible inhibitor of serine proteases. Also inhibits NADPH oxidase activation in vitro. Attenuates airway inflammation in a mouse model of airway allergy.
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| BCC1220 | Aprotinin |
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Competitive serine protease inhibitor. Reversibly binds to and blocks the enzymatic active site. Inhibits a range of serine proteases including trypsin, chymotrypsin, kallikrein and plasmin.
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| BCC1221 | Bestatin |
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Aminopeptidase inhibitor (Ki = 0.001 - 90 mM); inhibits enkephalin metabolism and leukotriene A4 hydrolase. Inhibits tumor cell proliferation.
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| BCC1222 | E-64 |
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Potent and irreversible cysteine protease inhibitor (IC50 values are 1.4, 2.5 and 4.1 nM for cathepsin K, L and S respectively. Also inhibits papain, calpain, cathepsin B and cathepsin H. Has no effect on serine proteases. Reduces HSC-3 tongue cancer cell invasion and induces oxidative stress and apoptosis in filarial parasites. Also inhibits autophagy-associated lysosomal degradation in vitro.
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| BCC1223 | Batimastat (BB-94) |
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Potent, broad spectrum MMP inhibitor (IC<sub>50</sub> values are 3, 4, 4, 6 and 20 nM for MMP -1, -2, -9, -7 and -3 respectively). Exhibits antiproliferative, anti-invasive and antimetastatic activity in human ovarian carcinoma xenografts <em>in vivo</em>.
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| BCC1227 | MG-132 |
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Potent cell-permeable inhibitor of proteasome (IC<sub>50</sub> = 100 nM) and calpain (IC<sub>50</sub> = 1.2 <span class='symbol'>μ</span>M). Inhibits TNF-<span class='symbol'>α</span>-induced NF-<span class='symbol'>κ</span>B activation and I<span class='symbol'>κ</span>B<span class='symbol'>α</span> degradation. Induces neurite outgrowth in PC12 cells and has anticancer properties <em>in vitro</em>.
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