Hot Natural Products & Bioactive Compounds
BioCrick offers high-purity natural products and bioactive compounds for scientific research. Our natural product collection includes compounds derived from plants, microorganisms and other biological sources and is widely used in pharmacological, biochemical and drug discovery research.
Natural products remain an important source of bioactive molecules and drug leads. BioCrick provides researchers with high-quality natural product compounds together with catalog numbers, product information and biological activity data.
Hot Products from BioCrick
Showing 57 - 64 of 9359 hot products
| Catalog No. | Product Name |
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| BCC1119 | Bumetanide |
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Bumetanide (Bumex) is a loop diuretic of the sulfamyl category to treat heart failure.
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| BCC1120 | XAV-939 |
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Potent tankyrase (TNKS) inhibitor (IC<sub>50</sub> values are 4 and 11 nM for TNKS2 and TNKS1 respectively). Antagonizes Wnt signaling via stimulation of <span class='symbol'>β</span>-catenin degradation and stabilization of axin. Inhibits proliferation of the <span class='symbol'>β</span>-catenin-dependent colon carcinoma cell line DLD-1. Promotes cardiomyogenic development in mesoderm progenitor cells.
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| BCC1122 | TRAM-34 |
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TRAM-34 is a highly selective blocker of intermediate-conductance calcium-activated K+ channel (IKCa1) (Kd=20 nM).
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| BCC1123 | SL-327 |
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Selective inhibitor of MEK1 and MEK2 (IC<sub>50</sub> values are 0.18 and 0.22 <span class='symbol'>μ</span>M respectively); blocks hippocampal LTP <em>in vitro</em>. Brain penetrant <em>in vivo</em>, blocking fear conditioning and learning in rats, and producing neuroprotection in mice, following systemic administration.
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| BCC1124 | PSI |
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Proteasome inhibitor; inhibits chymotrypsin-like activity of the proteasome. Causes dopaminergic cell death <em>in vitro</em>. Prevents activation of NF-<span class='symbol'>κ</span>B in response to TNF-<span class='symbol'>α</span> and okadaic acid by inhibiting I<span class='symbol'>κ</span>B-<span class='symbol'>α</span> degradation. Also inhibits NO production by LPS-activated macrophages.
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| BCC1126 | Z-VAD-FMK |
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Z-VAD-FMK is a cell-permeable, pan-caspase inhibitor.
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| BCC1127 | E 64d |
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Inhibitor of cathepsins B and L; also thought to inhibit calpain. Inhibits lysosomal proteases and interferes with autolysosomal digestion when used in combination with pepstatin A. Lysosome and cell permeable.
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| BCC1130 | 5-Azacytidine |
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5-Azacytidine is a nucleoside analogue of cytidine that specifically inhibits DNA methylation by trapping DNA methyltransferases.
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