Hot Natural Products & Bioactive Compounds
BioCrick offers high-purity natural products and bioactive compounds for scientific research. Our natural product collection includes compounds derived from plants, microorganisms and other biological sources and is widely used in pharmacological, biochemical and drug discovery research.
Natural products remain an important source of bioactive molecules and drug leads. BioCrick provides researchers with high-quality natural product compounds together with catalog numbers, product information and biological activity data.
Hot Products from BioCrick
Showing 25 - 32 of 9359 hot products
| Catalog No. | Product Name |
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| BCC1055 | SGX-523 |
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Potent and selective c-MET kinase inhibitor (IC<sub>50</sub> = 4nM). Exhibits minimal inhibition against a panel of 213 other protein kinases (at 1 <span class='symbol'>μ</span>M). Suppresses growth of tumor xenografts derived from human glioblastoma, lung and gastric cancer cells.
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| BCC1057 | Daptomycin |
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Lipopeptide, calcium-dependent antibiotic. Exhibits potent bacteriocidal activity against most gram-positive bacteria <em>in vitro</em> and <em>in vivo</em>, including antibiotic-resistant strains such as MRSA and VRE. Disrupts plasma membrane function; activity results in membrane depolarization leading to inhibition of protein, DNA and RNA synthesis.
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| BCC1058 | Lansoprazole |
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H<sup>+</sup>,K<sup>+</sup>-ATPase inhibitor (IC<sub>50</sub> = 6.3 <span class='symbol'>μ</span>M) that displays antisecretory and antiulcer activity. Inhibits gastric acid secretion (IC<sub>50</sub> = 0.09 <span class='symbol'>μ</span>M for histamine-induced acid formation) and reduces gastric lesion formation induced by a variety of ulcerative stimuli. Antibacterial against Helicobacter pylori <em>in vitro</em>. Also blocks swelling-dependent chloride channel (ICIswell) in NIH3T3 fibroblasts. More potent than omeprazole
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| BCC1063 | Letrozole |
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Potent, reversible non-steroidal aromatase inhibitor (IC50 = 11.5 nM). Displays antitumor effects in several animal models. Suppresses the endogenous aromatase-induced proliferation of MCF-7 cells.
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| BCC1064 | Gatifloxacin |
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Fluoroquinolone antibiotic. Inhibits bacterial type II topoisomerases (IC<sub>50</sub> values are 0.109 and 13.8 <span class='symbol'>μ</span>g/ml for <em>E.coli</em> DNA gyrase and <em>S.aureus</em> topoisomerase IV respectively). Displays potent activity against gram-positive and gram-negative bacteria. Stimulates short-term self-renewal in both human and mouse embryonic stem cells <em>in vitro</em>.
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| BCC1065 | Mosapride Citrate |
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5-HT<sub>4</sub> receptor agonist and 5-HT<sub>3</sub> receptor antagonist. Displays no activity at D<sub>2</sub>, <span class='symbol'>α</span><sub>1</sub>, <span class='symbol'>α</span><sub>2</sub>, 5-HT<sub>1</sub> and 5-HT<sub>2</sub> receptors. Gastroprokinetic agent; increases gastric emptying in rats and stimulates gastric motor actvity in conscious dogs.
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| BCC1067 | Zoledronic Acid |
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Potent bisphophonate farnesyl diphosphate (FPP) synthase inhibitor (IC50 = 20 nM). Inhibits osteoclast-mediated bone resorption. Also inhibits Ras signaling and tumor growth, and induces apoptosis in pancreatic cancer cells. Reverses epithelial-mesenchymal transition and inhibits breast cancer cell renewal via inactivation of NF-κB.
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| BCC1071 | Biapenem |
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Highly broad spectrum antibiotic agent. Stable against dehydropeptidase I. Shows bactericidal effects against Gram-negative and Gram-positive aerobic and anaerobic bacteria, including β-lactamase producing species in vivo.
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