Hot Natural Products & Bioactive Compounds
BioCrick offers high-purity natural products and bioactive compounds for scientific research. Our natural product collection includes compounds derived from plants, microorganisms and other biological sources and is widely used in pharmacological, biochemical and drug discovery research.
Natural products remain an important source of bioactive molecules and drug leads. BioCrick provides researchers with high-quality natural product compounds together with catalog numbers, product information and biological activity data.
Hot Products from BioCrick
Showing 9 - 16 of 9359 hot products
| Catalog No. | Product Name |
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| BCC1032 | Gap 26 |
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Peptide, corresponding to residues 63 - 75 of connexin 43, which is a gap junction blocker. Attenuates rhythmic contractile activity of rabbit arterial smooth muscle (IC50 = 28.4 μM). Also inhibits IP3-induced ATP release, without inhibiting gap junctional coupling in endothelial cells.
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| BCC1033 | Gap 27 |
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Peptide derived from connexin 43 that is a selective gap junction blocker. Attenuates ACh-induced arterial relaxation and reduces K+-mediated smooth muscle repolarization in endothelium-intact vessels in vitro.
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| BCC1034 | Dynamin inhibitory peptide |
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Peptide inhibitor of the GTPase dynamin; competitively blocks binding of dynamin to amphiphysin thus prevents endocytosis when administered intracellularly. Reduces GABA<sub>A</sub> receptor internalization and increases miniature ISPC amplitude and frequency in neurons expressing GABA<sub>A</sub> receptors. Cell-permeable version also available.
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| BCC1037 | Angiotensin 1/2 + A (2 - 8) |
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Potent endogenous vasoconstrictor peptide; derivative of angiotensin (Ang) II. Elicits pressor and renal vasoconstrictor effects in rodents via the AT<sub>1</sub> receptor; inhibited by Candesartan but not by AT<sub>2</sub> receptor ligands<em> in vivo</em>. Displays a similar affinity for AT<sub>1</sub> and AT<sub>2</sub> receptors as angiotensin II</a><em> in vitro</em> (K<sub>i</sub> values are 1.6 and 2.3 nM at AT<sub>1</sub> and AT<sub>2</sub> receptors); also increases inositol phosphate accumulation with a similar potency to Ang II (EC<sub>50</sub> = 6.7 nM).
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| BCC1040 | Parathyroid Hormone (1-34), bovine |
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Parathyroid hormone (PTH) receptor agonist. Increases calcium and inorganic phosphate levels in the serum of young rats. Increases osteocalcin concentrations in the serum of old rats without affecting calcium or phosphate levels.
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| BCC1041 | Peptide YY(3-36), PYY, human |
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NPY Y2 receptor agonist. Peripheral administration inhibits food intake in mice. This effect is greater when Peptide YY (3-36) is administered in combination with GLP-1 (7-36) (Cat.No. 2082).
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| BCC1042 | PKA inhibitor fragment (6-22) amide |
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Potent inhibitor of cAMP-dependent protein kinase (PKA) (Ki = 2.5 nM); derived from the active portion of the heat-stable PKA inhibitor protein PKI.
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| BCC1043 | Melanocyte stimulating hormone release inhibiting factor |
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Inhibitor of melanocyte-stimulating hormone (MSH) release. Blocks the release of <span class='symbol'>α</span>-MSH, increases brain dopamine levels and antagonizes physiological and behavioral opioid effects <em>in vivo</em>.
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