Hot Products
Hot products from BioCrick which is a professional high-purity natural products manufacturer are well known to scientists around the world because of their high purity and stability. Each product is a chemical compound or substance produced by a living organism—that is, found in nature. In the broadest sense, natural products include any substance produced by life.Natural products remain the best sources of drugs and drug leads, and this remains true today despite the fact that many pharmaceutical companies have deemphasized natural products research in favor of HTP screening of combinatorial libraries during the past 2 decades. From 1940s to date, 131 (74.8%) out of 175 small molecule anticancer drugs are natural product-based/inspired, with 85 (48.6%) being either natural products or derived therefrom. From 1981 to date, 79 (80%) out of 99 small molecule anticancer drugs are natural product-based/inspired, with 53 (53%) being either natural products or derived therefrom. Among the 20 approved small molecule New Chemical Entities (NCEs) in 2010, a half of them are natural products.
Hot products from the professional high-purity natural products manufacturer
| Cat.No. | Product Name |
|---|---|
| BCN8172 | Protostemonine |
| 1. Protostemonine has anti-inflammatory activity, it effectively attenuates LPS-induced inflammatory responses in vitro and in vivo; the beneficial effects are associated with the decreased phosphorylation of MAPK and AKT and the reduced expression of pro-inflammatory mediators, such as iNOS, NO and cytokines. 2. Protostemonine shows strong nematicidal activity against Panagrellus redivevus, with the IC50 value of 0.10 uM. 3. Protostemonine attenuates LPS/GalN-induced acute liver failure and upregulating HO-1 expression is implicated in its hepatoprotective activity. 4. Protostemonine shows significant antitussive activity in a citric acid-induced guinea pig cough model following peripheral administration. | |
| BCN8145 | Homomangiferin |
| 1. Homomangiferin shows antitumoural effects against MDA-MB-231 cells. | |
| BCN8144 | Myricetin 3-O-beta-D-glucopyranoside |
| 1. Myricetin 3-O-beta-D-glucopyranoside may have antioxidant, and anti-inflammatory activities. | |
| BCN8149 | Laricitrin 3-O-glucoside |
| 1. Laricitrin 3-O-glucoside has antioxidant property. | |
| BCN8166 | Heteroclitin D |
| 1. Heteroclitin D can inhibit L-type calcium channels. 2. Heteroclitin D might be a valuable antitumor promoter or chemopreventor. | |
| BCC1709 | Lucidin |
| 1. Lucidin and its derivatives are genotoxic, it is mutagenic at the hypoxanthine-guanine phosphoribosyl transferase gene locus. | |
| BCN8151 | 3alpha-dihydrocadambine |
| 1. 3alpha-Dihydrocadambine exhibits dose-dependent hypotensive and anti-hypertensive effects in anesthetized normotensive rats and in conscious spontaneously hypertensive rats. | |
| BCC6481 | Sanguinarine chloride |
| Sanguinarine chloride is a novel class of anti-Salmonella compounds, it could decrease the production of the SPI-1 type III secretion system main virulence proteins SipA and SipB and prevent the invasion of HeLa cells by Salmonella enterica serovar Typhimurium without affecting the growth of Salmonella. Sanguinarine chloride also shows cytotoxicity to cultured human cells from oral tissue. | |
