Hot Natural Products & Bioactive Compounds
BioCrick offers high-purity natural products and bioactive compounds for scientific research. Our natural product collection includes compounds derived from plants, microorganisms and other biological sources and is widely used in pharmacological, biochemical and drug discovery research.
Natural products remain an important source of bioactive molecules and drug leads. BioCrick provides researchers with high-quality natural product compounds together with catalog numbers, product information and biological activity data.
Hot Products from BioCrick
Showing 209 - 216 of 9359 hot products
| Catalog No. | Product Name |
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| BCC1647 | INCB024360 analogue |
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Potent indoleamine 2,3-dioxygenase (IDO) inhibitor (IC50 values are 19 and 67 nM in enzymatic activity and HeLa cell assays, respectively). Decreases kynurenine levels in plasma and reduces tumor growth in vivo. Cell membrane permeable.
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| BCC1655 | IRAK inhibitor 2 |
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IRAK inhibitor 2 is interleukin-1 receptor associated kinase inhibitor .
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| BCC1659 | IRAK-1-4 Inhibitor I |
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IRAK4 and IRAK1 inhibitor (IC<sub>50</sub> values are 0.2 and 0.3 <span class='symbol'>μ</span>M, respectively).
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| BCC1665 | IWP-2 |
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Inhibitor of Wnt processing and secretion. Inactivates PORCN, a membrane-bound O-acyltransferase (MBOAT), and selectively inhibits palmitoylation of Wnt. Blocks Wnt-dependent phosphorylation of Lrp6 receptor and Dvl2, and <span class='symbol'>β</span>-catenin accumulation. Suppresses self-renewal in R1 embryonic stem cells.
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| BCC1675 | kb NB 142-70 |
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Selective protein kinase D (PKD) inhibitor (IC<sub>50</sub> values are 28.3, 58.7 and 53.2 nM for PKD1, 2 and 3 respectively). More potent analog of CID 755673 with 7-fold greater inhibition. Inhibits prostrate cancer cell migration and invasion and reduces wound healing <em>in vitro</em>; displays prominent cytotoxic and anti-proliferative effects.
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| BCC1676 | KB-R7943 mesylate |
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Potent, selective inhibitor of the reverse mode of the Na+/Ca2+ exchanger (IC50 = 0.7 μM). Also inhibits the mitochondrial Ca2+ uniporter (MCU; IC50 = 5.5 μM). Does not affect Na+-dependent transport systems or ionotropic glutamate receptors.
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| BCC1678 | Ki20227 |
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Inhibitor of c-Fms tyrosine kinase (M-CSFR, CSF1R) (IC50 values are 2, 12, 217 and 451 nM for c-Fms, VEGFR-2, PDGFRβ and c-Kit respectively). Does not inhibit Flt3, EGFR or c-Src. Suppresses osteoclast differentiation and osteolysis in a rat bone metastasis model.
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| BCC1681 | KN-92 hydrochloride |
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KN-92 hydrochloride is a negative control for KN-93.
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