Hot Products
Hot products from BioCrick which is a professional high-purity natural products manufacturer are well known to scientists around the world because of their high purity and stability. Each product is a chemical compound or substance produced by a living organism—that is, found in nature. In the broadest sense, natural products include any substance produced by life.Natural products remain the best sources of drugs and drug leads, and this remains true today despite the fact that many pharmaceutical companies have deemphasized natural products research in favor of HTP screening of combinatorial libraries during the past 2 decades. From 1940s to date, 131 (74.8%) out of 175 small molecule anticancer drugs are natural product-based/inspired, with 85 (48.6%) being either natural products or derived therefrom. From 1981 to date, 79 (80%) out of 99 small molecule anticancer drugs are natural product-based/inspired, with 53 (53%) being either natural products or derived therefrom. Among the 20 approved small molecule New Chemical Entities (NCEs) in 2010, a half of them are natural products.
Hot products from the professional high-purity natural products manufacturer
| Cat.No. | Product Name |
|---|---|
| BCN7358 | Galeopsin |
| 1. Galeopsin shows potential anti-inflammatory activity by inhibiting proinflammatory cytokine TNF-α, it has anti-proliferative effect on several cancer cell lines. | |
| BCN7361 | Angeloylgomisin O |
| Angeloylgomisin O is a nartural product from Schisandra chinensis. | |
| BCN7368 | Neochebulagic acid |
| 1. 3,4',5-Trimethoxystilbene exhibits potent antitumor and anti-HCV activities without exhibiting cytotoxicity to human hepatocytes in vitro or in mice livers. 2. 3,4',5-Trimethoxystilbene acts as an inhibitor of tubulin polymerization. 3. 3,4',5-Trimethoxystilbene is a potent small molecule inducer of autophagy in human umbilical vascular endothelial cells (HUVECs) in the presence of serum. 4. 3,4',5-Trimethoxystilbene has anti-inflammatory activity, the ability of it to induce HO-1 expression may provide one of possible mechanisms of its anti-inflammatory action. 5. 3,4',5-Trimethoxystilbene exerts antiangiogenic and vascular-disrupting effects in zebrafish through the downregulation of VEGFR2 and cell-cycle modulation. 6. 3,4',5-Trimethoxystilbene exerts antiallergic and anti-mitotic properties. | |
| BCN7369 | Glycoursodeoxycholic acid |
| 1. Glycoursodeoxycholic acid shows protective effects in Barrett's esophagus cells by inhibiting oxidative stress. 2. Glycoursodeoxycholic acid and interleukin-10 modulate inflammation and cell survival, they may have potential benefits in reducing UCB-induced astrocyte immunostimulation and death. 3. Glycoursodeoxycholic acid reduces matrix metalloproteinase-9 and caspase-9 activation in a cellular model of superoxide dismutase-1 neurodegeneration. | |
| BCN7372 | ent-11alpha-Hydroxy-15-oxokaur-16-en-19-oic acid |
| 1. Ent-11alpha-Hydroxy-15-oxokaur-16-en-19-oic acid inhibits hepatocellular carcinoma in vitro and in vivo via stabilizing IkBα. 2. Ent-11alpha-Hydroxy-15-oxokaur-16-en-19-oic acid induces apoptosis of human malignant cancer cells. | |
| BCN7373 | 1-Methoxyberberine |
| 1. 1-Methoxyberberine chloride is a potential antifungal agent. | |
| BCN7378 | Longiferone B |
| 1. Longiferone B shows anti-inflammatory activity against NO release with IC50 values of 21.0 uM, it also suppresses the iNOS and COX-2 mRNA expression. | |
| BCN7379 | Pancixanthone A |
| 1. Pancixanthone A shows a significant antileishmanial activity against the promastigote forms of Leishmania mexicana and L. infantum and against the amastigote forms of L. infantum. 2. Pancixanthone A may have antimalarial activity. | |
