Hot Products

Hot products from BioCrick which is a professional high-purity natural products manufacturer are well known to scientists around the world because of their high purity and stability. Each product is a chemical compound or substance produced by a living organism—that is, found in nature. In the broadest sense, natural products include any substance produced by life.Natural products remain the best sources of drugs and drug leads, and this remains true today despite the fact that many pharmaceutical companies have deemphasized natural products research in favor of HTP screening of combinatorial libraries during the past 2 decades. From 1940s to date, 131 (74.8%) out of 175 small molecule anticancer drugs are natural product-based/inspired, with 85 (48.6%) being either natural products or derived therefrom. From 1981 to date, 79 (80%) out of 99 small molecule anticancer drugs are natural product-based/inspired, with 53 (53%) being either natural products or derived therefrom. Among the 20 approved small molecule New Chemical Entities (NCEs) in 2010, a half of them are natural products.

Hot products from the professional high-purity natural products manufacturer

Cat.No. Product Name
BCN7450 Aucuparin
1. Aucuparin is a phytoalexin. 2. Aucuparin exhibits potent inhibitory activity against fMLP-induced superoxide (O(*-)(2)) production by human neutrophils with the IC(50) value of 17.0+/-6.8 microM. 3. Aucuparin shows significant scavenging activity by the ABTS and FRAP assays.
BCN7451 Dalbergiphenol
1. Dalbergiphenol treatment can effectively prevent OVX-induced increase in bone loss and decrease in bone strength possibly by increasing osteoblastic activities and by decreasing osteoclastic activities. 2. Dalbergiphenol shows antiosteoporotic activity.
BCN7452 Dalbergin
1. Dalbergin exhibits similar bone conserving effect against bone-loss as estradiol treatment, it as a therapeutic candidate against postmenopausal osteoporosis. 2. Dalbergin prevents some effects of photoaging and maintain skin integrity by regulating the degradation of the extracellular matrix proteins.
BCN7455 Pyracrenic acid
1. Pyracrenic acid shows significant cytotoxic activities against human cancer cells COLO 205 and AGS. 2. Pyracrenic acid is a potent elastase inhibitor with an IC50 value of 1.5 mg/mL. 3. Pyracrenic acid shows DPPH radical scavenging activity.
BCN7457 Leucosceptoside A
1. Leucosceptoside A exhibits strong inhibitory capacity against α-glucosidase. 2. Leucosceptoside A shows angiotensin converting enzyme (ACE) inhibitory effect in a dose-dependent manner of which IC(50) value of 423+/-18.8 microg/ml, suggests that it has antihypertensive effect. 3. Leucosceptoside A shows inhibitory activity against PKCalpha with the IC50 value of 19.0 microM.
BCN7459 Citromycin
1. Citromycin, an antibiotic, has weakly cytotoxic.
BCC3805 Lithocholic Acid
Lithocholic acid is a toxic secondary bile acid, causes intrahepatic cholestasis, has tumor-promoting activity, its toxic effect can be protected after it activates the vitamin D receptor, PXR and FXR.Lithocholic acid is a vitamin D receptor (VDR) ligand, it can activate the VDR to block inflammatory signals in colon cells.
BCN7461 Neonuezhenide
1. Neonuezhenide exhibits strong antioxidant effect against hemolysis of red blood cells induced by free radicals.