Hot Products

Hot products from BioCrick which is a professional high-purity natural products manufacturer are well known to scientists around the world because of their high purity and stability. Each product is a chemical compound or substance produced by a living organism—that is, found in nature. In the broadest sense, natural products include any substance produced by life.Natural products remain the best sources of drugs and drug leads, and this remains true today despite the fact that many pharmaceutical companies have deemphasized natural products research in favor of HTP screening of combinatorial libraries during the past 2 decades. From 1940s to date, 131 (74.8%) out of 175 small molecule anticancer drugs are natural product-based/inspired, with 85 (48.6%) being either natural products or derived therefrom. From 1981 to date, 79 (80%) out of 99 small molecule anticancer drugs are natural product-based/inspired, with 53 (53%) being either natural products or derived therefrom. Among the 20 approved small molecule New Chemical Entities (NCEs) in 2010, a half of them are natural products.

Hot products from the professional high-purity natural products manufacturer

Cat.No. Product Name
BCN7617 Dehydrobruceantin
1. Dehydrobruceantin has anti-tuberculosis activity.
BCC5311 Bruceine A
1. Bruceine A and bruceine B show strong antitrypanosomal activities with IC(50) values in the range of 2.9-17.8nM. 2. Bruceine A has anthelmintic activity, it exhibits significant activity against Dactylogyrus intermedius with EC(50) values of 0.49 mg/L. 3. Bruceine A exhibits NF-κB p65 inhibition, and cytotoxic potential against HT-29, HeLa, and HL-60 cells . 4. Bruceine A has antibabesial activity, it can inhibit the in vitro growth of Babesia gibsoni in canine erythrocytes at lower concentration and kill the parasites within 24 hr at a concentration of 25 nM.
BCN7618 Bruceantin
1. Bruceantin has antiviral activity, it can inhibit pepper mottle virus in pepper. 2. Bruceantin is an effective agent in controlling the proliferation, viability and migration of multiple myeloma cancer stem cells (CSCs) as well as angiogenesis in vitro. 3. Bruceantin exhibits NF-κB p65 inhibition, and cytotoxic potential against HT-29, HeLa, and HL-60 cells . 4. Bruceantin shows high antimalarial activity.
BCN7619 Bruceine E
1. Bruceine E exhibits significant blood glucose concentration reduction activity, it might act as an insulin secretagogue.
BCN7620 Dehydrobruceine A
1. Dehydrobruceine A shows strong antitrypanosomal activities with IC(50) values in the range of 2.9-17.8nM.
BCN7621 Dehydrobruceantinol
1. Dehydrobruceantinol shows bitter taste and has antileukemic activity.
BCN7622 Bruceantinoside A
1. Bruceantinoside A has antileukemic activity.
BCN7623 Niazinin
1. Niazinin shows antileishmanial activity against promastigotes of Leishmania donavani, with an IC50 value of 5.25 microM.