Hot Products

Hot products from BioCrick which is a professional high-purity natural products manufacturer are well known to scientists around the world because of their high purity and stability. Each product is a chemical compound or substance produced by a living organism—that is, found in nature. In the broadest sense, natural products include any substance produced by life.Natural products remain the best sources of drugs and drug leads, and this remains true today despite the fact that many pharmaceutical companies have deemphasized natural products research in favor of HTP screening of combinatorial libraries during the past 2 decades. From 1940s to date, 131 (74.8%) out of 175 small molecule anticancer drugs are natural product-based/inspired, with 85 (48.6%) being either natural products or derived therefrom. From 1981 to date, 79 (80%) out of 99 small molecule anticancer drugs are natural product-based/inspired, with 53 (53%) being either natural products or derived therefrom. Among the 20 approved small molecule New Chemical Entities (NCEs) in 2010, a half of them are natural products.

Hot products from the professional high-purity natural products manufacturer

Cat.No. Product Name
BCN7716 Cinchonain IIa
1. Cinchonain IIa has antioxidant activity, it shows high radical scavenging activity and reducing power.
BCN7720 3'-Methoxydaidzin
1. 3'-Methoxydaidzin may be a potential neuroprotective substance in Gegen Qinlian decoction. 2. 3'-Methoxydaidzin has antioxidation activity.
BCN7721 Cinnamyl caffeate
1. Cinnamyl caffeate has cardiovascular protective effects, it can increase H9c2 cellular antioxidant potential, decrease intracellular calcium ion ([Ca2+]i) level, and prevent cell apoptosis. 2. Cinnamyl caffeate possesses potent NO inhibitory activity with the IC(50) value of 9.53 microM. 3. Cinnamyl caffeate possesses potent antiproliferative activity with the EC(50) value of 0.114 microM, toward colon 26-L5 carcinoma.
BCN7722 Moringin
1. Moringin is a modulator of neuroinflammation via the β-catenin-PPARγ axis, it can activate Wnt canonical pathway by inhibiting GSK3β in a mouse model of experimental autoimmune encephalomyelitis. 2. The combination of cannabidiol and moringin has anti-inflammatory, antioxidative, and anti-apoptotic effects. 3. Moringin is effective in inducing apoptosis through p53 and Bax activation and Bcl-2 inhibition, it demonstrates the antitumor efficacy in human malignant astrocytoma cells.
BCN7723 6-Deoxyisojacareubin
1. 6-Deoxyisojacareubin has antimicrobial activity. 2. 6-Deoxyisojacareubin shows moderate inhibitory activity against the QGY-7703 cell line, with the IC50 value of 9.65 uM. 3. 6-Deoxyisojacareubin possesses potency in the inhibition of protein kinase C (PKC).
BCN7726 Rauvovertine B
1. Rauvovertine B shows cytotoxicity in vitro against human tumor cell lines.
BCN7727 Rauvovertine C
1. Rauvovertine C shows cytotoxicity in vitro against human tumor cell lines.
BCN7728 Rauvovertine A
1. Rauvovertine A shows cytotoxicity in vitro against human tumor cell lines.