Hot Natural Products & Bioactive Compounds
BioCrick offers high-purity natural products and bioactive compounds for scientific research. Our natural product collection includes compounds derived from plants, microorganisms and other biological sources and is widely used in pharmacological, biochemical and drug discovery research.
Natural products remain an important source of bioactive molecules and drug leads. BioCrick provides researchers with high-quality natural product compounds together with catalog numbers, product information and biological activity data.
Hot Products from BioCrick
Showing 441 - 448 of 9359 hot products
| Catalog No. | Product Name |
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| BCC2380 | WAY 170523 |
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Potent and selective inhibitor of MMP-13 (IC50 values are 17, 945, > 1000 and > 10000 nM for MMP-13, MMP-9, TACE and MMP-1 respectively).
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| BCC2381 | BC 11 hydrobromide |
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Selective urokinase (uPA) inhibitor (IC<sub>50</sub> = 8.2 <span class='symbol'>μ</span>M). Exhibits no activity at 8 other related enzymes. Inhibits clot lysis with no effect on clot formation. Also decreases viability of MDA-MB231 breast cancer cells <em>in vitro</em>.
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| BCC2382 | 4-Chlorophenylguanidine hydrochloride |
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Potent and specific inhibitor of urokinase.
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| BCC2385 | Actinomycin D |
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Anti-neoplastic antibiotic. Inhibits RNA polymerase and is a potent inducer of apoptosis.
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| BCC2386 | C 75 |
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Synthetic inhibitor of fatty acid synthase (FASN); inhibits fatty acid synthesis in vitro and in vivo. Displays anorectic effects. Induces apoptosis in MCF-7 xenografts and exhibits anti-tumor activity.
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| BCC2388 | Mitomycin C |
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Antibiotic and antitumor agent. Covalently binds DNA forming intra- and interstrand crosslinks. Inhibits DNA synthesis. Also used for MEF/STO feeder layer preparation in stem cell culture.
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| BCC2389 | NSC 687852 (b-AP15) |
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Inhibitor of 19S regulatory particle associated deubiquitinating enzymes (DUBs), UCHL5 and USP14. Shows minimal inhibition of UCHL-1, UCHL-3, USP2, USP7, USP, BAP1 and proteasome activity. Induces apoptosis by cathepsin D-dependent caspase-cleavage (IC<sub>50</sub> = 0.5 <span class='symbol'>μ</span>M). Displays antitumor activity <em>in vivo</em>.
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| BCC2390 | Oncrasin 1 |
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Proapoptotic agent that induces abnormal nuclear aggregation of PKC<span class='symbol'>ι</span> and suppresses RNA transcription. Exhibits antiproliferative effects against various human tumor cell lines with K-Ras mutations (IC<sub>50</sub> ≤ 3 <span class='symbol'>μ</span>M) with minimal effects on normal epithelial cells and inhibits human xenograft growth by 75% <em>in vivo</em>.
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