Hot Natural Products & Bioactive Compounds
BioCrick offers high-purity natural products and bioactive compounds for scientific research. Our natural product collection includes compounds derived from plants, microorganisms and other biological sources and is widely used in pharmacological, biochemical and drug discovery research.
Natural products remain an important source of bioactive molecules and drug leads. BioCrick provides researchers with high-quality natural product compounds together with catalog numbers, product information and biological activity data.
Hot Products from BioCrick
Showing 497 - 504 of 9359 hot products
| Catalog No. | Product Name |
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| BCC2445 | UNC 926 hydrochloride |
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Methyl-lysine (Kme) reader domain inhibitor; binds to the MBT domain of the L3MBTL1 protein (K<sub>d</sub> = 3.9 <span class='symbol'>μ</span>M). Selectively inhibits the L3MBTL1<sub>3XMBT</sub>-H4K20me1 interaction in a peptide pull down assay.
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| BCC2446 | PIM-1 Inhibitor 2 |
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Potent Pim-1 kinase inhibitor (Ki = 91 nM).
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| BCC2447 | TCS PIM-1 1 |
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ATP-competitive Pim-1 kinase inhibitor that displays selectivity over Pim-2 and MEK1/2 (IC50 values are 50, > 20000 and > 20000 nM for Pim-1, Pim-2 and MEK1/2 respectively).
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| BCC2448 | 4-HQN |
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1. Some 4-quinazolinone derivatives have antiplatelet activity.
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| BCC2449 | BYK 204165 |
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Potent and selective poly(ADP-ribose) polymerase (PARP)-1 inhibitor (pIC50 values are 5.38 and 7.35 for PARP-2 and PARP-1 respectively).
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| BCC2450 | BYK 49187 |
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PARP-1 and PARP-2 inhibitor (pIC50 values are 8.36 and 7.50 for cell-free recombinant PARP-1 and murine PARP-2 respectively). Displays potent inhibitory activity against human PARP-1 in cell-free and cellular assays in vitro; reduces myocardial infarct size in vivo.
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| BCC2451 | DR 2313 |
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Competitive inhibitor of poly(ADP-ribose) polymerase (PARP) (IC<sub>50</sub> values are 0.20 and 0.24 <span class='symbol'>μ</span>M for PARP-1 and PARP-2 respectively). Neuroprotective; reduces neuronal cell death in models of cerebral ischemia <em>in vivo</em> and <em>in vitro</em>. Brain penetrant.
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| BCC2452 | EB 47 |
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Potent inhibitor of PARP-1 (IC50 = 45 nM). Reduces infarct volume in both a rat transient middle cerebral arterial occlusion model and a cardiac reperfusion model.
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