Hot Products
Hot products from BioCrick which is a professional high-purity natural products manufacturer are well known to scientists around the world because of their high purity and stability. Each product is a chemical compound or substance produced by a living organism—that is, found in nature. In the broadest sense, natural products include any substance produced by life.Natural products remain the best sources of drugs and drug leads, and this remains true today despite the fact that many pharmaceutical companies have deemphasized natural products research in favor of HTP screening of combinatorial libraries during the past 2 decades. From 1940s to date, 131 (74.8%) out of 175 small molecule anticancer drugs are natural product-based/inspired, with 85 (48.6%) being either natural products or derived therefrom. From 1981 to date, 79 (80%) out of 99 small molecule anticancer drugs are natural product-based/inspired, with 53 (53%) being either natural products or derived therefrom. Among the 20 approved small molecule New Chemical Entities (NCEs) in 2010, a half of them are natural products.
Hot products from the professional high-purity natural products manufacturer
| Cat.No. | Product Name |
|---|---|
| BCN2210 | (S)-(+)-Abscisic acid |
| Abscisic acid (ABA) is a ubiquitous hormone that regulates plant growth, development and responses to environmental stresses, plays a crucial role in the plant's response to both biotic and abiotic stress. Treatment with low concentrations of abscisic acid ( 10 to 100 microM) induced an antioxidative defence response against oxidative damage, but a high concentration of ABA (1,000 microM) induced an excessive generation of AOS and led to an oxidative damage in plant cells. | |
| BCN2211 | 11Beta-hydroxyprogesterone |
| The progesterone derivatives 11 alpha- and 11 beta-hydroxyprogesterone are potent inhibitors of 11 beta-hydroxysteroid dehydrogenase (isoforms 1 and 2) in vitro and can confer mineralocorticoid activity on corticosterone in the rat in vivo. 11beta-Hydroxyprogesterone acts as a mineralocorticoid agonist in stimulating Na+ absorption in mammalian principal cortical collecting duct cells. | |
| BCN2212 | 3-Hydroxybutyric acid |
| 3-Hydroxybutyric acid is a ketone body and acts as an indicator of energy balance and a central regulator of energy homeostasis. 3-Hydroxybutyric acid has anesthetic actions, which are due to the metabolite's abilities to alter physical properties of cell membranes, leading to indirect effects on membrane protein function. | |
| BCN2213 | 3-Nitro-L-tyrosine |
| 3-Nitro-L-tyrosine,an oxidative stress marker associated with neurodegenerative disorders.3-Nitro-L-tyrosine could as solid-phase extraction (SPE) sorbent material. | |
| BCN1485 | NG,NG-Dimethylarginine dihydrochloride |
| 1. NG,NG-Dimethylarginine dihydrochloride is a reversible inhibitor of nitric oxide synthetase in vivo and in vitro. | |
| BCN2214 | Dipalmitin |
| Dipalmitin has templating effects on soft palm mid fraction crystals. | |
| BCN2215 | Arachidonic acid |
| Arachidonic acid is 1 of only 2 unsaturated fatty acids retained in the ovaries of crustaceans and an inhibitor of HR97g, a nuclear receptor expressed in adult ovaries. Arachidonic acid induces retinal arteriolar vasodilation by inhibiting subcellular Ca(2+)-signaling activity in retinal arteriolar myocytes, most likely through a mechanism involving the inhibition of L-type Ca(2+)-channel activity. Arachidonic acid causes an increase in free cytoplasmic calcium concentration ([Ca2+]i) in differentiated skeletal multinucleated myotubes C2C12 and does not induce calcium response in C2C12 myoblasts. | |
| BCN2216 | Pimaricin |
| Pimaricin is an effective, broad spectrum antifungal, it also exhibits reduced (oral and topical) toxicity to humans, which is probably associated with the lack of effects on mammalian cell membranes. | |
