Hot Products

Hot products from BioCrick which is a professional high-purity natural products manufacturer are well known to scientists around the world because of their high purity and stability. Each product is a chemical compound or substance produced by a living organism—that is, found in nature. In the broadest sense, natural products include any substance produced by life.Natural products remain the best sources of drugs and drug leads, and this remains true today despite the fact that many pharmaceutical companies have deemphasized natural products research in favor of HTP screening of combinatorial libraries during the past 2 decades. From 1940s to date, 131 (74.8%) out of 175 small molecule anticancer drugs are natural product-based/inspired, with 85 (48.6%) being either natural products or derived therefrom. From 1981 to date, 79 (80%) out of 99 small molecule anticancer drugs are natural product-based/inspired, with 53 (53%) being either natural products or derived therefrom. Among the 20 approved small molecule New Chemical Entities (NCEs) in 2010, a half of them are natural products.

Hot products from the professional high-purity natural products manufacturer

Cat.No. Product Name
BCN2235 Estriol
Estriol (E3), an endogenous estrogen predominantly produced during human pregnancy, is an antagonist of the G-protein coupled estrogen receptor in estrogen receptor-negative breast cancer cells. E3 can blunt the postprandial glycemic surge in rats through modulating the level of intestinal glucose transporters. E3 exerts a mitogenic effect on T-47D and MCF-7 cells at concentrations of 10(-9)M (288 pg/ml) and higher.
BCN2236 Estriol 3-sulfate
1. Estriol 3-sulfate acts through the hydrolyzed E3, E3-17-S is inactive because it is not hydrolyzed, so Estriol 3-sulfate can play an important role in the biological responses of this mammary cancer cell line.
BCN2237 Estriol 17-sulfate
1. Estriol 17-sulfate stimulates PR very significantly in the MCF-7 human mammary cancer cell line E3 and E3-3-S.
BCN2239 Estriol 3-glucuronide
1. Estradiol-3-glucuronide, estradiol-17beta-glucuronide, estriol-3-glucuronide , estrone glucuronide, estriol-16alpha-glucuronide, and pregnanediol-3alpha-glucuronide are immunoreactive metabolites of the major urinary estrogens, they have used to ovulation detection methods.
BCN2241 7-Methoxy-1-tetralone
1. 7-Methoxy-1-tetralone may have insecticidal activity.
BCN2242 7-Methoxy-1-naphthylacetonitrile
1. 7-Methoxy-1-naphthyl-acetonitrile is an important intermediate in the preparation of anti-depression drugs.
BCN2245 1-Indanone
1-Indanone thiosemicarbazones coordinated to palladium(II) is more cytotoxic than those complexed with platinum(II); although platinum(II) is more selective for leukemic cells and has potential to treat hematological malignancies.
BCN2247 Propargyl benzenesulfonate
1. Propargyl benzenesulfonate improves the SEI formation process.