Hot Natural Products & Bioactive Compounds
BioCrick offers high-purity natural products and bioactive compounds for scientific research. Our natural product collection includes compounds derived from plants, microorganisms and other biological sources and is widely used in pharmacological, biochemical and drug discovery research.
Natural products remain an important source of bioactive molecules and drug leads. BioCrick provides researchers with high-quality natural product compounds together with catalog numbers, product information and biological activity data.
Hot Products from BioCrick
Showing 537 - 544 of 9359 hot products
| Catalog No. | Product Name |
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| BCC2500 | Tenofovir |
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Selectively inhibits HIV reverse transcriptase (RNA-dependent DNA polymerase). Prevents cytotoxicity in SIV-infected C-8166 cells <em>in vitro </em> (IC<sub>50</sub> = 1.5 <span class='symbol'>μ</span>M). Antiviral agent.
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| BCC2501 | Risedronate Sodium |
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Orally active biphosphonate that inhibits farnesyl diphosphate (FPP) synthase (IC50 = 100 nM). Exhibits antiproliferative and proapoptotic activity in numerous tumor cell lines and inhibits osteoclast-mediated bone resorption in vivo.
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| BCC2502 | Sumatriptan Succinate |
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5-HT1 receptor agonist (Ki values are 17, 27 and 100 nM at 5-HT1D, 5-HT1B and 5-HT1A receptors respectively). Antimigraine agent.
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| BCC2503 | Ranolazine 2HCl |
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Antianginal agent with antiarrhythmic properties that acts as a partial fatty acid oxidation inhibitor. Activates pyruvate dehydrogenase in ischemic myocytes to promote glucose oxidation, switching substrate utilization from fatty acids to glucose. Also shown to inhibit late I<sub>Na</sub> and I<sub>Kr</sub> currents.
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| BCC2504 | Repaglinide |
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Kir6 (KATP) channel blocker that binds with high affinity for SUR1 when co-expressed with Kir6.2 (Kd = 0.42 nM). Antidiabetic glucose regulator with hypoglycaemic effect in vivo.
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| BCC2505 | Prazosin HCl |
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<span class='symbol'>α</span><sub>1</sub> and <span class='symbol'>α</span><sub>2B</sub>-adrenoceptor antagonist. Also a potent antagonist at the melatonin MT<sub>3</sub> receptor (K<sub>i</sub> = 10.2 nM). Also available as part of the <span class='symbol'>α</span><sub>1</sub>-Adrenoceptor and Mixed Adrenergic.
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| BCC2506 | Tianeptine sodium |
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Selective facilitator of 5-HT uptake <em>in vitro</em> and <em>in vivo</em>. Has no affinity for a wide range of receptors, including 5-HT and dopamine (IC<sub>50</sub> > 10 <span class='symbol'>μ</span>M) and has no effect on noradrenalin or dopamine uptake. Antidepressant, analgesic and neuroprotective following systemic administration <em>in vivo</em>.
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| BCC2508 | TSU-68 (SU6668,Orantinib) |
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ATP-competitive PDGFR, VEGF and FGFR inhibitor (IC<sub>50</sub> values are 0.06, 2.43, 3.04 and > 100 <span class='symbol'>μ</span>M at PDGFR<span class='symbol'>β</span>, VEGFR2, FGFR1 and EGFR respectively). Inhibits proliferation of HUVEC and NIH3T3 cells <em>in vitro</em> (IC<sub>50</sub> values are 0.41, 9.3 and 16.5 <span class='symbol'>μ</span>M for VEGF, FGF and PDGF-stimulated growth respectively) and induces > 75% growth inhibition against a broad range of tumor types <em>in vivo</em>. Exhibits antiangiogenic, anti-inflammatory, antimetastatic and proapoptotic activity and is orally active.
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