Hot Products
Hot products from BioCrick which is a professional high-purity natural products manufacturer are well known to scientists around the world because of their high purity and stability. Each product is a chemical compound or substance produced by a living organism—that is, found in nature. In the broadest sense, natural products include any substance produced by life.Natural products remain the best sources of drugs and drug leads, and this remains true today despite the fact that many pharmaceutical companies have deemphasized natural products research in favor of HTP screening of combinatorial libraries during the past 2 decades. From 1940s to date, 131 (74.8%) out of 175 small molecule anticancer drugs are natural product-based/inspired, with 85 (48.6%) being either natural products or derived therefrom. From 1981 to date, 79 (80%) out of 99 small molecule anticancer drugs are natural product-based/inspired, with 53 (53%) being either natural products or derived therefrom. Among the 20 approved small molecule New Chemical Entities (NCEs) in 2010, a half of them are natural products.
Hot products from the professional high-purity natural products manufacturer
| Cat.No. | Product Name |
|---|---|
| BCN7735 | Desmethylrocaglamide |
| 1. Desmethylrocaglamide has insecticidal activity. 2. Desmethylrocaglamide is a novel inducer of cellular differentiation using HL-60 promyelocytic cells, it may be a drug for the prevention and therapy of cancer. | |
| BCN7736 | Geissoschizine methyl ether |
| 1. Geissoschizine methyl ether is a potent serotonin ₁A receptor agonist and candidate for amelioration of aggressiveness and sociality by yokukansan. 2. Geissoschizine methyl ether has vasorelaxant effect, which is composed of two different mechanisms: endothelial dependency with nitric oxide and endothelial independency with voltage-dependent Ca(2+)-channel blocking. 3. Geissoschizine methyl ether has third-generation antipsychotic-like actions at the dopamine and serotonin receptors. 4. Geissoschizine methyl ether is a strong acetylcholinesterase (AChE) inhibitor, it inhibited 50% of AChE activity at concentrations of 3.7 ± 0.3 ug/mL. 5. Geissoschizine methyl ether protects neurons from oxidative toxicity by shifting energy metabolism from mitochondrial respiration to glycolysis. | |
| BCN7738 | Cinchonain IIb |
| 1. Cinchonain IIb shows high radical scavenging activity and reducing power. | |
| BCN7743 | Trachelosiaside |
| 1. Trachelosiaside shows moderate activity against lipoxygenase. | |
| BCN7744 | Persicogenin |
| 1. Persicogenin has anticancer activity, it can inhibit the proliferation of mouse tsFT210 cancer cells, it mainly inhibits cell cycle at the G2/M phase in a dose-dependent manner. 2. Persicogenin shows the antimutagenic effect against AFB1. 3. Persicogenin possesses antileishmanial activity. | |
| BCN7745 | Thalrugosaminine |
| 1. Thalrugosaminine shows promising antibacterial activity with MIC values of 64-128ug/ml and Staphylococcus species is the most sensitive strains. 2. Thalrugosaminine possesses hypotensive activity in rabbits and is active against Mycobacterium smegmatis. | |
| BCN7749 | 1-Monopalmitin |
| 1. 1-Monopalmitin has dielectric properties. 2. 1-Monopalmitin inhibits the P-glycoprotein activity in intestinal Caco-2 cells. | |
| BCN7751 | 2'-Hydroxy-4'-methylacetophenone |
| 1. 2'-Hydroxy-4'-methylacetophenone has acaricidal activity. | |
