Hot Products
Hot products from BioCrick which is a professional high-purity natural products manufacturer are well known to scientists around the world because of their high purity and stability. Each product is a chemical compound or substance produced by a living organism—that is, found in nature. In the broadest sense, natural products include any substance produced by life.Natural products remain the best sources of drugs and drug leads, and this remains true today despite the fact that many pharmaceutical companies have deemphasized natural products research in favor of HTP screening of combinatorial libraries during the past 2 decades. From 1940s to date, 131 (74.8%) out of 175 small molecule anticancer drugs are natural product-based/inspired, with 85 (48.6%) being either natural products or derived therefrom. From 1981 to date, 79 (80%) out of 99 small molecule anticancer drugs are natural product-based/inspired, with 53 (53%) being either natural products or derived therefrom. Among the 20 approved small molecule New Chemical Entities (NCEs) in 2010, a half of them are natural products.
Hot products from the professional high-purity natural products manufacturer
| Cat.No. | Product Name |
|---|---|
| BCN7696 | Debilon |
| 1. Debilon shows cytotoxic activity against P-388 cells. | |
| BCN7698 | Viscumneoside III |
| 1. Viscumneoside III demonstrates high tyrosinase inhibition, suggests that it can be utilized in skin whitening cosmetics. | |
| BCN7700 | Kanshone B |
| 1. Kanshone B shows inhibitory activity against LPS-induced NO production with the IC(50) value of 4.6-21.6 uM. | |
| BCN7704 | 4,2'-Dihydroxy-4'-methoxychalcone |
| 1. 4,2'-Dihydroxy-4'-methoxychalcone shows allergy-preventive effects. | |
| BCN7705 | Ailanthoidol |
| 1. Ailanthoidol has anti-inflammatory activity, it inhibits inflammatory reactions by macrophages and protects mice from endotoxin shock. 2. Ailanthoidol possesses potential as a chemopreventive agent against tumor promotion. 3. Ailanthoidol has anti-adipogenic activity, it effectively suppresses adipogenesis and that it exerts its role mainly through the significant down-regulation of PPARγ and C/EBPα expression. | |
| BCN7712 | Ursolic aldehyde |
| 1. Ursolic aldehyde can inhibit phosphatase of regenerating liver-3, with the IC(50) value of 50 +/- 0.3 mu M. | |
| BCN7714 | 5-O-Methylgenistein |
| 1. 5-O-Methylgenistein may have hepatoprotective property on the model of toxic hepatitis induced by carbon tetrachloride damage. 2. 5-O-Methylgenistein may show free radical scavenging activity. | |
| BCN7715 | 1-O-Acetylbritannilactone |
| 1. 1-O-Acetylbritannilactone has anticancer activity, it combined with gemcitabine elicits a potent apoptosis of lung cancer cell and hence it has the potential to be developed as a chemotherapeutic agent. 2. 1-O-Acetylbritannilactone may serve as a novel therapeutic intervention for various cardiovascular diseases, including chronic ischemia, by regulating VEGF signaling and modulating angiogenesis. 3. 1-O-Acetylbritannilactone suppresses angiogenesis and lung cancer cell growth possibly via regulating the VEGFR-Src-FAK signaling. 4. 1-O-Acetylbritannilactone exhibits anti-melanogenic activity by suppression of tyrosinase expression via ERK and Akt signaling, it may act as potent natural skin-lightening agents. 5. 1-O-Acetylbritannilactone is a potent inhibitor of LPS-stimulated VSMC inflammatory responses through blockade of NF-kappaB activity and inhibition of inflammatory gene COX-2 expression. | |
