Hot Products
Hot products from BioCrick which is a professional high-purity natural products manufacturer are well known to scientists around the world because of their high purity and stability. Each product is a chemical compound or substance produced by a living organism—that is, found in nature. In the broadest sense, natural products include any substance produced by life.Natural products remain the best sources of drugs and drug leads, and this remains true today despite the fact that many pharmaceutical companies have deemphasized natural products research in favor of HTP screening of combinatorial libraries during the past 2 decades. From 1940s to date, 131 (74.8%) out of 175 small molecule anticancer drugs are natural product-based/inspired, with 85 (48.6%) being either natural products or derived therefrom. From 1981 to date, 79 (80%) out of 99 small molecule anticancer drugs are natural product-based/inspired, with 53 (53%) being either natural products or derived therefrom. Among the 20 approved small molecule New Chemical Entities (NCEs) in 2010, a half of them are natural products.
Hot products from the professional high-purity natural products manufacturer
| Cat.No. | Product Name |
|---|---|
| BCN7653 | Hedycoronen A |
| 1. Hedycoronen A and hedycoronen B are potent inhibitors of LPS-stimulated interleukin-6 (IL-6) and IL-12 p40, with IC(50) ranging from 4.1±0.2 to 9.1±0.3 uM, they also show moderate inhibitory activity on the tumor necrosis factor-α (TNF-α) production with IC(50) values of 46.0±1.3 and 12.7±0.3 uM, suggests that they have the potential anti-inflammatory benefits. | |
| BCN7655 | 12-O-Methylcarnosic acid |
| 1. 12-O-Methylcarnosic acid is effective preventing gastric lesions. 2. 12-O-Methylcarnosic acid has antioxidant activity. 3. 12-O-Methylcarnosic acid can suppress melanin production with downregulation of tyrosinase expression in HMV-II melanoma cells. 4. 12-O-Methylcarnosic acid is able to significantly activate peroxisome proliferator-activated receptor (PPAR)γ, it may have anti-diabetic activity. | |
| BCN7660 | Junicedric acid |
| 1. Junicedric acid has gastroprotective effects. | |
| BCN7664 | (-)-Praeruptorin A |
| 1. (-)-Praeruptorin A has anti-inflammatory, anti-contractile and anti-hyperplasia activities. 2. (-)-Praeruptorin A resensitizes Pgp-mediated MDR (Pgp-MDR) cancer cells to cancer drugs. 3. (-)-Praeruptorin A exerts distinct relaxant effects on isolated rat aorta rings dependent on endothelium and nitric oxide synthesis. 4. (-)-Praeruptorin A can significantly suppress airway inflammation and airway remodeling induced by ovalbumin challenge, and is a potential candidate for the treatment of asthma. | |
| BCN7666 | Gardenoin J |
| 1. Gardenoin J may show cytotoxic effects on five human tumor cell lines. | |
| BCN7672 | 7alpha,15-Dihydroxydehydroabietic acid |
| 1. 7alpha,15-Dihydroxydehydroabietic acid may exhibit significant cytotoxic activity. | |
| BCC1314 | 7-Epi 10-Desacetyl Paclitaxel |
| 7-Epi-10-deacetyltaxol shows IC50 values of 0.085 nM, against HeLa cells. | |
| BCN7679 | Hyuganin D |
| 1. Hyuganin D can inhibit LPS-induced NO and/or TNF-alpha production in mouse peritoneal macrophages. | |
