Hot Natural Products & Bioactive Compounds
BioCrick offers high-purity natural products and bioactive compounds for scientific research. Our natural product collection includes compounds derived from plants, microorganisms and other biological sources and is widely used in pharmacological, biochemical and drug discovery research.
Natural products remain an important source of bioactive molecules and drug leads. BioCrick provides researchers with high-quality natural product compounds together with catalog numbers, product information and biological activity data.
Hot Products from BioCrick
Showing 393 - 400 of 9359 hot products
| Catalog No. | Product Name |
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| BCC2315 | JNJ-1661010 |
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Selective, reversible inhibitor of fatty acid amide hydrolase (FAAH) (IC<sub>50</sub> = 12 nM). Brain penetrant and active <em>in vivo</em>.
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| BCC2317 | Fluvastatin Sodium |
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Orally active, potent and competitive HMG-CoA reductase inhibitor (IC<sub>50</sub> = 40 -100 nM at human liver microsomes). Inhibits vascular smooth muscle proliferation <em>in vitro</em> (IC<sub>50</sub> = 70 nM) and exhibits antihypercholesterolemic and antioxidant activity <em>in vivo</em>.
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| BCC2319 | Atorvastatin Calcium |
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Potent HMG-CoA reductase inhibitor (IC<sub>50</sub> = 8 nM). Reduces circulating LDL-C by inhibiting cholesterol biosynthesis and inducing expression of LDL receptors. Inhibits smooth muscle cell proliferation <em>in vitro</em> and exhibits antinociceptive effects in the inflammatory hypernociception model.
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| BCC2321 | Pravastatin sodium |
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Water-soluble, competitive inhibitor of 3-hydroxy-3-methyl coenzyme A (HMG-CoA) reductase. Potently blocks cholesterol synthesis <em>in vivo</em> (K<sub>i</sub>~ 1 nM) and displays cardioprotective properties.
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| BCC2322 | Moclobemide (Ro 111163) |
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Reversible monoamine oxidase A (MOA-A) inhibitor.
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| BCC2323 | Ferrostatin-1 (Fer-1) |
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Selective inhibitor of erastin</a> induced ferroptosis (EC<sub>50</sub> = 60 nM). Specifically inhibits Ras selective lethal compound -induced death, but not cell death induced by other oxidative lethal compounds and apoptosis-inducing agents. Inhibits ferroptosis in cancer cells; also inhibits glutamate-induced cell death in organotypic rat brain slices. Prevents erastin induced accumulation of cytosolic and lipid reactive oxygen species.
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| BCC2324 | URB597 |
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Potent and selective fatty acid amide hydrolase (FAAH) inhibitor (IC50 values are 3 and 5 nM in human liver and rat brain, respectively). Exhibits no significant inhibitory activity against a variety of receptors, ion channels and enzymes, including human cannabinoid receptors and rat monoacylglycerol lipase. Displays antiallodynic and antihyperalgesic activity in an inflammatory pain model.
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| BCC2326 | PF-3845 |
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Selective fatty acid amide hydrolase (FAAH) inhibitor (K<sub>i</sub> = 0.23 <span class='symbol'>μ</span>M). Reduces inflammatory pain via a cannabinoid receptor-dependent mechanism. Highly efficacious and selective <em>in vivo</em>. Displays no activity at FAAH-2 (IC<sub>50</sub> >10 <span class='symbol'>μ</span>M).
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