BCN4306(-)-Usnic acid(+)-Usnic acid is isolated from isolated from lichens, binds at the ATP-binding pocket of mTOR, and inhibits mTORC1/2 activity. (+)-Usnic acid inhibits the phosphorylation of mTOR downstream effectors: Akt (Ser473), 4EBP1, S6K, induces autophay, with anti-cancer activity.(CAS NO.:7562-61-0)
BCN4588Broussonin CBotanical source: The branch of Broussonetia papyrifera(CAS NO.:76045-49-3)
BCN32651-Dehydro-6-gingerdioneBotanical source: The rhizomes of Zingber officinale Rosc.(CAS NO.:76060-35-0)
BCN6297DihydrocurcuminDihydrocurcumin, a major metabolites of curcumin, reduces lipid accumulation and oxidative stress. Dihydrocurcumin regulates mRNA and protein expression levels of SREBP-1C, PNPLA3 and PPARα, increases protein expression levels of pAKT and PI3K, and reduced the levels of cellular NO and ROS via Nrf2 signaling pathways.(CAS NO.:76474-56-1)
BCN4828Erythrabyssin IIBotanical source: The herbs of Erythrina arborescens(CAS NO.:77263-06-0)
BCN8226Carasinol BBotanical source: The herb of Carex humilis Leyss(CAS NO.:777857-86-0)
BCN4032Mulberrofuran CBotanical source: The root bark of Morus alba L.(CAS NO.:77996-04-4)
BCN6514HannokinolBotanical source: The herbs of Alnus japonica(CAS NO.:79120-40-4)
BCN35921,7-Diphenyl-4-hepten-3-oneBotanical source: The rhizomes of Alpinia officinarum Hance(CAS NO.:79559-59-4)
BCN21591,2,3,6-Tetragalloylglucose1,2,3,6-Tetragalloylglucose is a potent UDP glucuronosyltransferase 1 family, polypeptide A1 (UGT1A1) inhibitor, with a Ki of 1.68 μM.(CAS NO.:79886-50-3)
BCN1056HelicidHelicid (Helicide) is a major constituent of Helicia nilgirica Bedd. Helicid has been used to treat psychoneurosis for its sedative-hypnotic and analgesic properties.(CAS NO.:80154-34-3)
BCN4573Dehydro-δ-tocopherolBotanical source: The roots of Stemona sessilifolia(CAS NO.:802909-72-4)
BCN3414Tinnevellin glucosideTinnevellin glucoside, a naphthalene glycoside, isolated from Cassia senna leaves and pods.(CAS NO.:80358-06-1)
BCN4344Grifolic acidBotanical source: The Cylindrocarpon ianthothele var. majus(CAS NO.:80557-12-6)
BCN3756Gnetumontanin BBotanical source: The herbs of Gnetum montanum(CAS NO.:809237-87-4)
BCN4355Daurichromenic acidBotanical source: The herbs of Rhododendron dauricum(CAS NO.:82003-90-5)
BCN3600CoeloninBotanical source: The herbs of Bletilla striata(CAS NO.:82344-82-9)
BCN13402,3,5,4'-Tetrahydroxyl diphenylethylene-2-O-glucoside2,3,4',5-tetrahydroxystilbene 2-O-D-glucoside isolats from the roots of Polygonum species, inhibits the formation of 5-HETE, HHT and thromboxane B2, although less strongly.(CAS NO.:82373-94-2)
BCN663711-O-GalloylbergeninBotanical source: The aerial parts of Bergenia ligulata.(CAS NO.:82958-44-9)