13-Epimanool

CAS# 1438-62-6

13-Epimanool

Catalog No. BCN4862----Order now to get a substantial discount!

Product Name & Size Price Stock
13-Epimanool: 5mg $615 In Stock
13-Epimanool: 10mg Please Inquire In Stock
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Quality Control of 13-Epimanool

Number of papers citing our products

Chemical structure

13-Epimanool

3D structure

Chemical Properties of 13-Epimanool

Cas No. 1438-62-6 SDF Download SDF
PubChem ID 129317223 Appearance Powder
Formula C20H34O M.Wt 290.5
Type of Compound Diterpenoids Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name (3S)-5-[(1R,4aR,8aS)-5,5,8a-trimethyl-2-methylidene-3,4,4a,6,7,8-hexahydro-1H-naphthalen-1-yl]-3-methylpent-1-en-3-ol
SMILES CC1(CCCC2(C1CCC(=C)C2CCC(C)(C=C)O)C)C
Standard InChIKey CECREIRZLPLYDM-HNBVOPMISA-N
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of 13-Epimanool

The herbs of Salvia prionitis

Biological Activity of 13-Epimanool

TargetsAntifection

13-Epimanool Dilution Calculator

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13-Epimanool Molarity Calculator

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Preparing Stock Solutions of 13-Epimanool

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 3.4423 mL 17.2117 mL 34.4234 mL 68.8468 mL 86.0585 mL
5 mM 0.6885 mL 3.4423 mL 6.8847 mL 13.7694 mL 17.2117 mL
10 mM 0.3442 mL 1.7212 mL 3.4423 mL 6.8847 mL 8.6059 mL
50 mM 0.0688 mL 0.3442 mL 0.6885 mL 1.3769 mL 1.7212 mL
100 mM 0.0344 mL 0.1721 mL 0.3442 mL 0.6885 mL 0.8606 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on 13-Epimanool

Labdane diterpenoid glycosides from Aster veitchianus.[Pubmed:17372956]

Chem Biodivers. 2007 Mar;4(3):531-8.

Four new labdane-type rhamnopyranosides derived from 13-Epimanool, compounds 1-4, with differently acetylated sugar moieties, were isolated from A. veitchianus. Their structures and absolute configurations were elucidated by chemical transformation, spectroscopic and mass-spectrometric analyses (IR, 1D- and 2D-NMR, HR-ESI-MS), as well as by single-crystal X-ray diffraction (compound 1). The isolates 2-4 were investigated for their cytotoxic properties against cultured human hepatoma (SMMC-7721), ovarian neoplasm (HO-8910), and leukemia (HL-60) cells, and for their antibacterial activities against Escherichia coli, Bacillus subtilis, and Staphylococcus aureus.

Phytochemicals from Cunninghamia konishii Hayata act as antifungal agents.[Pubmed:22129092]

J Agric Food Chem. 2012 Jan 11;60(1):124-8.

The aims of the present study were to isolate and identify the antifungal compounds from the ethanolic extract of Cunninghamia konishii wood and to evaluate their antifungal activities against wood decay fungi. The results showed that the n-Hex soluble fraction of the ethanolic extract from C. konishii wood had an excellent inhibitory effect against Lenzites betulina, Trametes versicolor, Laetiporus sulphureus, and Gloeophyllum trabeum, with IC(50) values of 33, 46, 62, and 49 mug/mL, respectively. By following the bioactivity-guided fractionation procedure, four sesquiterpenes, T-cadinol, cedrol, T-muurolol, and (-)-epi-cedrol, and three diterpenes, 13-epi-manool, cis-abienol, and isoabienol, were identified from the active subfractions. Among the main constituents of the ethanolic extract from C. konishii, T-cadinol, cedrol, and T-muurolol efficiently inhibited the growth of four wood-rot fungi at the concentration of 100 mug/mL, with antifungal indices of 51.4-100.0%, 68.3-100.0%, and 39.5-100.0%, respectively. Results of this study show that the ethanolic extract of C. konishii wood may be considered as a potent source of T-cadinol, cedrol, and T-muurolol as new natural antifungal agents.

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