Guaiol

CAS# 489-86-1

Guaiol

Catalog No. BCN6619----Order now to get a substantial discount!

Product Name & Size Price Stock
Guaiol: 5mg $104 In Stock
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Quality Control of Guaiol

Number of papers citing our products

Chemical structure

Guaiol

3D structure

Chemical Properties of Guaiol

Cas No. 489-86-1 SDF Download SDF
PubChem ID 227829 Appearance Powder
Formula C15H26O M.Wt 222.4
Type of Compound Sesquiterpenoids Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name 2-[(3S,5R,8S)-3,8-dimethyl-1,2,3,4,5,6,7,8-octahydroazulen-5-yl]propan-2-ol
SMILES CC1CCC(CC2=C1CCC2C)C(C)(C)O
Standard InChIKey TWVJWDMOZJXUID-SDDRHHMPSA-N
Standard InChI InChI=1S/C15H26O/c1-10-5-7-12(15(3,4)16)9-14-11(2)6-8-13(10)14/h10-12,16H,5-9H2,1-4H3/t10-,11-,12+/m0/s1
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Guaiol

The roots of Ferula ferulaeoides.

Biological Activity of Guaiol

Description1. Guaiol has insecticidal activity, it shows significant inhibition of aphids at a concentration of 70 mg/L, it also shows good contact activities against the 4th instar larvae of Mythimna separate and 3rd instar larvae of Plutella xylostella, with LD50 values of 0.07 and 8.9 mg/larva, as well as fumigation activity against the 4th instar larvae of M. separata and adult Musca domestica, with LC50 values of 3.5 microL/L and 16.9 microL/L, respectively. 2. (-)-Guaiol is a biocatalyst.

Guaiol Dilution Calculator

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Guaiol Molarity Calculator

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Preparing Stock Solutions of Guaiol

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 4.4964 mL 22.482 mL 44.964 mL 89.9281 mL 112.4101 mL
5 mM 0.8993 mL 4.4964 mL 8.9928 mL 17.9856 mL 22.482 mL
10 mM 0.4496 mL 2.2482 mL 4.4964 mL 8.9928 mL 11.241 mL
50 mM 0.0899 mL 0.4496 mL 0.8993 mL 1.7986 mL 2.2482 mL
100 mM 0.045 mL 0.2248 mL 0.4496 mL 0.8993 mL 1.1241 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on Guaiol

Biotransformation of (-)-guaiol by Eurotium rubrum as a biocatalyst.[Pubmed:16753905]

Nat Prod Res. 2006 Jul 10;20(8):731-4.

The biotransformation of (-)-Guaiol (1) has been investigated by using plant parasite fungus, Eurotium rubrum. Compound 1 was oxidized at the C-2 position, and transformed to pancherione.

Guaiol--a naturally occurring insecticidal sesquiterpene.[Pubmed:24354171]

Nat Prod Commun. 2013 Oct;8(10):1353-4.

The dichloromethane fraction of Ferula ferulaeoides was analyzed by GC and GC-MS, and thirty-four compounds were identified. The main component in the fraction, Guaiol (37.0%) was separated by chromatographic methods and identified from spectroscopic data, including 1H and 13C NMR, and X-ray crystallographic diffraction. Guaiol showed significant inhibition of aphids at a concentration of 70 mg/L. It also showed good contact activities against the 4th instar larvae of Mythimna separate and 3rd instar larvae of Plutella xylostella, with LD50 values of 0.07 and 8.9 mg/larva, as well as fumigation activity against the 4th instar larvae ofM. separata and adult Musca domestica, with LC50 values of 3.5 microL/L and 16.9 microL/L, respectively.

Description

Guaiol is a sesquiterpene alcohol that has been found in several traditional Chinese medicinal plants and has antiproliferative, pro-autophagic, insect repellent, and insecticidal biological activities.

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