vibo-Quercitol

CAS# 488-76-6

vibo-Quercitol

Catalog No. BCN5594----Order now to get a substantial discount!

Product Name & Size Price Stock
vibo-Quercitol: 5mg $69 In Stock
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Quality Control of vibo-Quercitol

Number of papers citing our products

Chemical structure

vibo-Quercitol

3D structure

Chemical Properties of vibo-Quercitol

Cas No. 488-76-6 SDF Download SDF
PubChem ID 441438 Appearance Powder
Formula C6H12O5 M.Wt 164.2
Type of Compound Miscellaneous Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name (1R,2S,4R,5R)-cyclohexane-1,2,3,4,5-pentol
SMILES C1C(C(C(C(C1O)O)O)O)O
Standard InChIKey IMPKVMRTXBRHRB-RSVSWTKNSA-N
Standard InChI InChI=1S/C6H12O5/c7-2-1-3(8)5(10)6(11)4(2)9/h2-11H,1H2/t2-,3-,4-,5+,6?/m1/s1
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of vibo-Quercitol

The herb of Itea yunnanensis Franch.

Biological Activity of vibo-Quercitol

Description(-)-vibo-Quercitol is a carbaglycosylamine glycosidase inhibitor.

Protocol of vibo-Quercitol

Structure Identification
J Nat Prod. 2007 Mar;70(3):493-7. Epub 2007 Mar 9.

Synthesis of valiolamine and some precursors for bioactive carbaglycosylamines from (-)-vibo-quercitol produced by biogenesis of myo-inositol.[Pubmed: 17346079]

A convenient and practical synthesis of valiolamine (4) and its related carbaglycosylamine glycosidase inhibitors from (-)-vibo-Quercitol (13), a compound readily produced by biogenesis of myo-inositol (9), is described.

Bioorg Med Chem Lett. 2011 Dec 1;21(23):7189-92.

Transformation of quercitols into 4-methylenecyclohex-5-ene-1,2,3-triol derivatives, precursors for the chemical chaperones N-octyl-4-epi-β-valienamine (NOEV) and N-octyl-β-valienamine (NOV).[Pubmed: 22001090]

(+)-proto-Quercitol (1) and (-)-vibo-Quercitol (2), both of which could be readily prepared by the bioconversion of myo-inositol, were successfully converted into the corresponding 4-methylenecyclohex-5-ene-1,2,3-triol derivatives. These compounds were demonstrated to be suitable precursors, preserving their configurations, for bioactive carba-aminosugars such as the potent chemical chaperone drug candidates, N-octyl-4-epi-β-valienamine (NOEV, 3) and N-octyl-β-valienamine (NOV, 4).

vibo-Quercitol Dilution Calculator

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vibo-Quercitol Molarity Calculator

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Preparing Stock Solutions of vibo-Quercitol

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 6.0901 mL 30.4507 mL 60.9013 mL 121.8027 mL 152.2533 mL
5 mM 1.218 mL 6.0901 mL 12.1803 mL 24.3605 mL 30.4507 mL
10 mM 0.609 mL 3.0451 mL 6.0901 mL 12.1803 mL 15.2253 mL
50 mM 0.1218 mL 0.609 mL 1.218 mL 2.4361 mL 3.0451 mL
100 mM 0.0609 mL 0.3045 mL 0.609 mL 1.218 mL 1.5225 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on vibo-Quercitol

Transformation of quercitols into 4-methylenecyclohex-5-ene-1,2,3-triol derivatives, precursors for the chemical chaperones N-octyl-4-epi-beta-valienamine (NOEV) and N-octyl-beta-valienamine (NOV).[Pubmed:22001090]

Bioorg Med Chem Lett. 2011 Dec 1;21(23):7189-92.

(+)-proto-Quercitol (1) and (-)-vibo-Quercitol (2), both of which could be readily prepared by the bioconversion of myo-inositol, were successfully converted into the corresponding 4-methylenecyclohex-5-ene-1,2,3-triol derivatives. These compounds were demonstrated to be suitable precursors, preserving their configurations, for bioactive carba-aminosugars such as the potent chemical chaperone drug candidates, N-octyl-4-epi-beta-valienamine (NOEV, 3) and N-octyl-beta-valienamine (NOV, 4).

Synthesis of valiolamine and some precursors for bioactive carbaglycosylamines from (-)-vibo-quercitol produced by biogenesis of myo-inositol.[Pubmed:17346079]

J Nat Prod. 2007 Mar;70(3):493-7.

A convenient and practical synthesis of valiolamine (4) and its related carbaglycosylamine glycosidase inhibitors from (-)-vibo-Quercitol (13), a compound readily produced by biogenesis of myo-inositol (9), is described.

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