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N-Acetylsulfanilyl chloride

CAS# 121-60-8

N-Acetylsulfanilyl chloride

2D Structure

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3D structure

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N-Acetylsulfanilyl chloride

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Chemical Properties of N-Acetylsulfanilyl chloride

Cas No. 121-60-8 SDF Download SDF
PubChem ID 8481 Appearance Powder
Formula C8H8ClNO3S M.Wt 233.7
Type of Compound N/A Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name 4-acetamidobenzenesulfonyl chloride
SMILES CC(=O)NC1=CC=C(C=C1)S(=O)(=O)Cl
Standard InChIKey GRDXCFKBQWDAJH-UHFFFAOYSA-N
Standard InChI InChI=1S/C8H8ClNO3S/c1-6(11)10-7-2-4-8(5-3-7)14(9,12)13/h2-5H,1H3,(H,10,11)
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

N-Acetylsulfanilyl chloride Dilution Calculator

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N-Acetylsulfanilyl chloride Molarity Calculator

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Preparing Stock Solutions of N-Acetylsulfanilyl chloride

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 4.279 mL 21.395 mL 42.7899 mL 85.5798 mL 106.9748 mL
5 mM 0.8558 mL 4.279 mL 8.558 mL 17.116 mL 21.395 mL
10 mM 0.4279 mL 2.1395 mL 4.279 mL 8.558 mL 10.6975 mL
50 mM 0.0856 mL 0.4279 mL 0.8558 mL 1.7116 mL 2.1395 mL
100 mM 0.0428 mL 0.2139 mL 0.4279 mL 0.8558 mL 1.0697 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on N-Acetylsulfanilyl chloride

Synthesis of hapten and production of a monoclonal antibody against a derivative of L-hydroxyproline, a special amino acid in hydrolyzed animal protein.[Pubmed:23030435]

J Environ Sci Health B. 2013;48(1):9-15.

China's government has prohibited the addition of simply hydrolyzed animal protein from solid leather waste into milk. The objective of this study was to produce a monoclonal antibody against L-hydroxyproline, a special amino acid in hydrolyzed animal protein. L-hydroxyproline was derivatized with N-Acetylsulfanilyl chloride and 5-chlorovaleric acid to synthesize the haptens HP1 and HP2. Then, two immunogens from the two haptens were prepared to produce the antibodies. Results showed that only HP1 was able to stimulate the animal immune system and generate the specific antibody to L-hydroxyproline (as the formation of HP1). The obtained monoclonal antibody from HP1 and the heterologous coating hapten HP2 were incorporated into a competitive indirect enzyme linked immunosorbent assay (ELISA) to determine the antibody's specificity and sensitivity. The IC(50) and the limit of detection for HP1 were 0.16 mug/mL and 0.05 mug/mL respectively. The antibody showed low crossreactivity to parental L-hydroxyproline and showed negligible crossreactivity to D-hydroxyproline and other amino acids. The monoclonal antibody was therefore suitable for the development of an immunoassay to monitor the simply hydrolyzed animal protein from solid leather waste in foodstuffs with L-hydroxyproline as the target analyte.

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