NordalberginCAS# 482-82-6 |
Quality Control & MSDS
3D structure
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Number of papers citing our products
| Cas No. | 482-82-6 | SDF | Download SDF |
| PubChem ID | 5320203 | Appearance | Powder |
| Formula | C15H10O4 | M.Wt | 254 |
| Type of Compound | Coumarins | Storage | Desiccate at -20°C |
| Solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | ||
| Chemical Name | 6,7-dihydroxy-4-phenylchromen-2-one | ||
| SMILES | C1=CC=C(C=C1)C2=CC(=O)OC3=CC(=C(C=C23)O)O | ||
| Standard InChIKey | TZRNJQYCOSMOJS-UHFFFAOYSA-N | ||
| Standard InChI | InChI=1S/C15H10O4/c16-12-6-11-10(9-4-2-1-3-5-9)7-15(18)19-14(11)8-13(12)17/h1-8,16-17H | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
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| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
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| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
| In vitro | Effect of coumarins on HL-60 cell differentiation.[Pubmed: 10953319]Anticancer Res. 2000 Jul-Aug;20(4):2505-12.
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Nordalbergin Dilution Calculator
Nordalbergin Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 3.937 mL | 19.685 mL | 39.3701 mL | 78.7402 mL | 98.4252 mL |
| 5 mM | 0.7874 mL | 3.937 mL | 7.874 mL | 15.748 mL | 19.685 mL |
| 10 mM | 0.3937 mL | 1.9685 mL | 3.937 mL | 7.874 mL | 9.8425 mL |
| 50 mM | 0.0787 mL | 0.3937 mL | 0.7874 mL | 1.5748 mL | 1.9685 mL |
| 100 mM | 0.0394 mL | 0.1969 mL | 0.3937 mL | 0.7874 mL | 0.9843 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
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Effect of coumarins on HL-60 cell differentiation.[Pubmed:10953319]
Anticancer Res. 2000 Jul-Aug;20(4):2505-12.
Twenty-eight coumarins, including 7 furocoumarins, were examined for their activity of induction of terminal differentiation of human promyelocytic leukemia cells (HL-60) by nitro blue tetrazolium (NBT) reducing, nonspecific esterase, specific esterase and phagocytic activities. Esculetin, Nordalbergin, 6,7-dihydroxy-4-methylcoumarin and imperatorin had strong activity among the coumarins examined. HL-60 cells treated with these coumarins differentiated into mature monocyte/macrophage. The structure-activity relationship established from the results revealed that 6,7-dihydroxy moiety had an important role in the induction of differentiation of HL-60.
