AricineCAS# 482-91-7 |
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3D structure
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Number of papers citing our products
| Cas No. | 482-91-7 | SDF | Download SDF |
| PubChem ID | 251575 | Appearance | Powder |
| Formula | C22H26N2O4 | M.Wt | 382.5 |
| Type of Compound | Alkaloids | Storage | Desiccate at -20°C |
| Solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | ||
| SMILES | CC1C2CN3CCC4=C(C3CC2C(=CO1)C(=O)OC)NC5=C4C=C(C=C5)OC | ||
| Standard InChIKey | DTDADHMBRZKXSC-GKASHWOUSA-N | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
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| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
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| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
| Description | Aricine has cytotoxicity. |
| In vitro | In vitro cytotoxicity testing of natural products using guinea‐pig ear keratinocytes[Reference: WebLink]Phytotherapy Research,1988,2(1):25-29.
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| Structure Identification | Natural Product Communications, 2012, 7(11):1441-1444.A new monoterpenoid oxindole alkaloid from Hamelia patens micropropagated plantlets.[Reference: WebLink]
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Aricine Dilution Calculator
Aricine Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 2.6144 mL | 13.0719 mL | 26.1438 mL | 52.2876 mL | 65.3595 mL |
| 5 mM | 0.5229 mL | 2.6144 mL | 5.2288 mL | 10.4575 mL | 13.0719 mL |
| 10 mM | 0.2614 mL | 1.3072 mL | 2.6144 mL | 5.2288 mL | 6.5359 mL |
| 50 mM | 0.0523 mL | 0.2614 mL | 0.5229 mL | 1.0458 mL | 1.3072 mL |
| 100 mM | 0.0261 mL | 0.1307 mL | 0.2614 mL | 0.5229 mL | 0.6536 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
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Alkaloids from Rauwolfia cubana Stem Bark.[Pubmed:17262416]
Planta Med. 1989 Jun;55(3):283-5.
Six indole alkaloids, tetrahydroalstonine, Aricine, 16- EPI-affinine, ajmaline, amerovolfine, and amerovolficine have been isolated from the ethanolic extract of the stem bark of RAUWOLFIA CUBANA A. DC. Amerovolfine ( N(alpha)-demethylaccedine) and amerovolficine (16-demethoxy-carbonylpagicerine) are new alkaloids related to 16- EPI-affinine, and their structures have been determined by spectroscopic analysis.
Application of pH-zone-refining countercurrent chromatography for the separation of indole alkaloids from Aspidosperma rigidum Rusby.[Pubmed:24192149]
J Chromatogr A. 2013 Dec 6;1319:166-71.
Species of Aspidosperma (Apocynaceae) are characterized by the occurrence of indole alkaloids, but few recent reports on Aspidosperma rigidum Rusby chemical constituents were found. The present work shows the application of pH-zone refining countercurrent chromatography on the separation of alkaloids from the barks of A. rigidum. In this study, the dichloromethane extract was fractionated with the solvent system composed of methyl-tert-butyl ether and water with different concentrations of the retainer triethylamine in the organic stationary phase and formic or hydrochloric acids as eluters in the aqueous mobile phase, in order to evaluate the most suitable condition. In each experiment, from circa 200mg of the dichloromethane extract of A. rigidum, three major alkaloids were isolated and identified as 3alpha-Aricine (circa 17mg), isoreserpiline (ca. 22mg) and 3beta-reserpiline (ca. 40mg), with relative purity of 79%, 89% and 82% respectively, in a one-step separation of 2h. Two of them - 3alpha-Aricine and isoreserpiline - were isolated and identified for the first time in this species.
A new monoterpenoid oxindole alkaloid from Hamelia patens micropropagated plantlets.[Pubmed:23285803]
Nat Prod Commun. 2012 Nov;7(11):1441-4.
Chemical studies on Hamelia patens (Rubiaceae) micropropagated plantlets allowed production of a new monoterpenoid oxindole alkaloid, named (-)-hameline (7), together with eight known alkaloids, tetrahydroalstonine (1), Aricine (2), pteropodine (3), isopteropodine (4), uncarine F (5), speciophylline (6), palmirine (8), and rumberine (9). The structure of the new alkaloid was assigned on the basis of 1D and 2D NMR spectroscopy, mass spectrometry, and molecular modeling.
