UNC 926 hydrochlorideInhibitor of methyl lysine reader domain CAS# 1184136-10-4 |
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Quality Control & MSDS
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Chemical structure
3D structure
| Cas No. | 1184136-10-4 | SDF | Download SDF |
| PubChem ID | 61041645 | Appearance | Powder |
| Formula | C16H21BrN2O | M.Wt | 337.3 |
| Type of Compound | N/A | Storage | Desiccate at -20°C |
| Solubility | DMSO : ≥ 155 mg/mL (459.60 mM) *"≥" means soluble, but saturation unknown. | ||
| Chemical Name | (3-bromophenyl)-(4-pyrrolidin-1-ylpiperidin-1-yl)methanone | ||
| SMILES | C1CCN(C1)C2CCN(CC2)C(=O)C3=CC(=CC=C3)Br | ||
| Standard InChIKey | OWGLFIKZKQOYHZ-UHFFFAOYSA-N | ||
| Standard InChI | InChI=1S/C16H21BrN2O/c17-14-5-3-4-13(12-14)16(20)19-10-6-15(7-11-19)18-8-1-2-9-18/h3-5,12,15H,1-2,6-11H2 | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
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| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
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| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
| Description | Methyl-lysine (Kme) reader domain inhibitor; binds to the MBT domain of the L3MBTL1 protein (Kd = 3.9 μM). Selectively inhibits the L3MBTL13XMBT-H4K20me1 interaction in a peptide pull down assay. |
UNC 926 hydrochloride Dilution Calculator
UNC 926 hydrochloride Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 2.9647 mL | 14.8236 mL | 29.6472 mL | 59.2944 mL | 74.118 mL |
| 5 mM | 0.5929 mL | 2.9647 mL | 5.9294 mL | 11.8589 mL | 14.8236 mL |
| 10 mM | 0.2965 mL | 1.4824 mL | 2.9647 mL | 5.9294 mL | 7.4118 mL |
| 50 mM | 0.0593 mL | 0.2965 mL | 0.5929 mL | 1.1859 mL | 1.4824 mL |
| 100 mM | 0.0296 mL | 0.1482 mL | 0.2965 mL | 0.5929 mL | 0.7412 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
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Methyl-lysine reader antagonist; binds to the MBT domain of the L3MBTL1 protein (Kd = 3.9 μM). Selectively inhibits, in a dose-dependent manner, the interaction between L3MBTL13XMBT-H4K20me1 in a peptide pull down assay.
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UNC-926 is a methyl-lysine (Kme) reader domain inhibitor; inhibits L3MBTL1 with an IC50 of 3.9 μM.
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