Z-Arg(NO2)-OHCAS# 2304-98-5 |
| Cas No. | 2304-98-5 | SDF | File under preparation. |
| PubChem ID | 102781 | Appearance | Powder |
| Formula | C14H19N5O6 | M.Wt | 353.3 |
| Type of Compound | N/A | Storage | Desiccate at -20°C |
| Synonyms | Z-Arg(NO2)-OH; 2304-98-5; Z-L-Arg(NO2)-OH; N-cbz-n-nitro-l-arginine | ||
| Solubility | Soluble in water or 1% acetic acid | ||
| Chemical Name | 5-[[amino(nitramido)methylidene]amino]-2-(phenylmethoxycarbonylamino)pentanoic acid | ||
| SMILES | C1=CC=C(C=C1)COC(=O)NC(CCCN=C(N)N[N+](=O)[O-])C(=O)O | ||
| Standard InChIKey | BZPCSFNCKORLQG-UHFFFAOYSA-N | ||
| Standard InChI | InChI=1S/C14H19N5O6/c15-13(18-19(23)24)16-8-4-7-11(12(20)21)17-14(22)25-9-10-5-2-1-3-6-10/h1-3,5-6,11H,4,7-9H2,(H,17,22)(H,20,21)(H3,15,16,18) | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
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| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
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| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
Quality Control & MSDS
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Z-Arg(NO2)-OH Dilution Calculator
Z-Arg(NO2)-OH Molarity Calculator
Similar Structures
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| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 2.8305 mL | 14.1523 mL | 28.3046 mL | 56.6091 mL | 70.7614 mL |
| 5 mM | 0.5661 mL | 2.8305 mL | 5.6609 mL | 11.3218 mL | 14.1523 mL |
| 10 mM | 0.283 mL | 1.4152 mL | 2.8305 mL | 5.6609 mL | 7.0761 mL |
| 50 mM | 0.0566 mL | 0.283 mL | 0.5661 mL | 1.1322 mL | 1.4152 mL |
| 100 mM | 0.0283 mL | 0.1415 mL | 0.283 mL | 0.5661 mL | 0.7076 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
Z-Arg(NO2)-OH
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Studies on lactam formation during coupling procedures of N alpha-N omega-protected arginine derivatives.[Pubmed:8738983]
Pept Res. 1996 Mar-Apr;9(2):88-91.
We evaluated the quantity of delta-lactam generated during the synthesis of arginine-containing dipeptides using Z-Arg(Tos)-OH, Boc-Arg(Tos)-OH, Fmoc-Arg(Boc)2-OH and Fmoc-Arg(Pmc)-OH and assayed several carboxyl-activating procedures for coupling the protected arginines to different amino components. We observed significant amounts of delta-lactam during the synthesis of Z-Arg(Tos)-methyl ester and Z-Arg(Tos)-amide, as well as of Boc-Arg(Tos)-chloromethyl ketone. The mixed anhydride coupling procedure and the di-Boc-protecting guanidino group induced more delta-lactam formation than any other coupling or NG-protection method. The amide, benzyl, 4-(NO2)-benzyl and methyl alpha-carboxyl-protected amino acids generated more delta-lactam than did those protected by tertbutyl or N2H2-Boc. So far it has not been possible to propose a general mechanism for delta-lactam formation or a process that completely abolishes it. Therefore, this side reaction should be considered almost inevitable. Its minimization requires examination of arginine-containing peptides in each specific synthesis.
Z-Arg(NO2)-OH (CAS 2304-98-5) is a natural product offered by BioCrick for research applications. Customers can buy or order Z-Arg(NO2)-OH from BioCrick, a supplier and manufacturer of research chemicals, with product specifications, purity, packaging, and pricing information available upon request.
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