Ajugasterone CCAS# 23044-80-6 |
Quality Control & MSDS
Number of papers citing our products
Chemical structure
3D structure
Cas No. | 23044-80-6 | SDF | Download SDF |
PubChem ID | 441826 | Appearance | Powder |
Formula | C27H44O7 | M.Wt | 480.64 |
Type of Compound | Steroids | Storage | Desiccate at -20°C |
Solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | ||
Chemical Name | (2S,3R,5R,9R,10R,11R,13R,14S,17S)-17-[(2R,3R)-2,3-dihydroxy-6-methylheptan-2-yl]-2,3,11,14-tetrahydroxy-10,13-dimethyl-2,3,4,5,9,11,12,15,16,17-decahydro-1H-cyclopenta[a]phenanthren-6-one | ||
SMILES | CC(C)CCC(C(C)(C1CCC2(C1(CC(C3C2=CC(=O)C4C3(CC(C(C4)O)O)C)O)C)O)O)O | ||
Standard InChIKey | LQGNCUXDDPRDJH-UKTRSHMFSA-N | ||
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
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About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
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Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. |
Description | Ajugasterone C shows significant inhibitory effect at 100 mg/kg dose on rat paw oedema development due to carrageenan-induced inflammation in Sprague Dawley rats. |
Targets | Immunology & Inflammation related |
In vivo | Phytoecdysteroids from the stem bark of Vitex doniana and their anti-inflammatory effects.[Pubmed: 23150078 ]Planta Med. 2013 Jan;79(1):52-9.With reference to the ethnopharmacological significance of Vitex doniana Sweet (Lamiaceae) leaves in the treatment of stomach and rheumatic pains as well as inflammatory disorders, biological studies on its stem bark extracts have also reported anti-inflammatory and analgesic activities, with no attempt to identify the active components.
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Ajugasterone C Dilution Calculator
Ajugasterone C Molarity Calculator
1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
1 mM | 2.0806 mL | 10.4028 mL | 20.8056 mL | 41.6112 mL | 52.014 mL |
5 mM | 0.4161 mL | 2.0806 mL | 4.1611 mL | 8.3222 mL | 10.4028 mL |
10 mM | 0.2081 mL | 1.0403 mL | 2.0806 mL | 4.1611 mL | 5.2014 mL |
50 mM | 0.0416 mL | 0.2081 mL | 0.4161 mL | 0.8322 mL | 1.0403 mL |
100 mM | 0.0208 mL | 0.104 mL | 0.2081 mL | 0.4161 mL | 0.5201 mL |
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. |
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CAS No.:
Phytoecdysteroids from the stem bark of Vitex doniana and their anti-inflammatory effects.[Pubmed:23150078]
Planta Med. 2013 Jan;79(1):52-9.
With reference to the ethnopharmacological significance of Vitex doniana Sweet (Lamiaceae) leaves in the treatment of stomach and rheumatic pains as well as inflammatory disorders, biological studies on its stem bark extracts have also reported anti-inflammatory and analgesic activities, with no attempt to identify the active components. Chromatographic and spectroscopic procedures identified three new phytoecdysteroids: 21-hydroxyshidasterone (1), 11beta-hydroxy-20-deoxyshidasterone (2), and 2,3-acetonide-24-hydroxyecdysone (3) from the stem bark methanol extracts along with known ecdysteroids shidasterone (4), Ajugasterone C (5), 24-hydroxyecdysone (6), and 11beta,24-hydroxyecdysone (7). The compounds (1-7) showed significant (p = 0.05) inhibitory effect at 100 mg/kg dose on rat paw oedema development due to carrageenan-induced inflammation in Sprague Dawley rats. These results suggest a possible contribution of ecdysteroids to the anti-inflammatory effect of some V. doniana stem bark extracts.