Phosphodiesterases - others

Cat.No. Product Name Information

BCC6954 Siguazodan Siguazodan (SKF 94836) is a potent, selective and orally active phosphodiesterase III (PDE-III) inhibitor with an IC50 of 117 nM. Siguazodan increases cAMP accumulation in intact platelets with an EC50 of 18.88 μM. Siguazodan also inhibits phenylephrine-induced 5-HT release with an IC50 value of 4.2 μM.

BCC7463 CP 80633

BCC6215 Piclamilast

BCC7645 RS 25344 hydrochloride

BCC7814 CDP 840 hydrochloride Potent and selective PDE4 inhibitor

BCC7549 Mesopram

BCC7190 YM 976 YM 976

BCC7188 ICI 63197

BCC7502 IBMX IBMX is a broad-spectrum phosphodiesterase (PDE) inhibitor, with IC50s of 6.5, 26.3 and 31.7 μM for PDE3, PDE4 and PDE5, respectively. IBMX

BCC6638 Ro 20-1724

BCC5803 T 0156 hydrochloride

BCC7871 Gisadenafil besylate Gisadenafil besylate (UK 369003-26) is a specific, orally active phosphodiesterase 5 (PDE5) inhibitor with an IC50 of 3.6 nM and prevents degradation of cyclic guanosine monophosphate (cGMP).

BCC6648 Etazolate hydrochloride

BCC6843 Cilostamide Cilostamide is a selective and potent PDE3 inhibitor, with IC50s of 27 nM and 50 nM for PDE3A and PDE3B, respectively, and has antithrombotic and anti-intimal hyperplastic activity.

BCC7940 BC 11-38

BCC7155 Enoximone

BCC6692 MMPX MMPX

BCC6645 MY-5445 MY-5445 is a specific phosphodiesterase type 5 (PDE5) inhibitor. MY-5445 selectively inhibits cGMP PDE with a Ki of 1.3 μM. MY-5445

BCC7333 Trequinsin hydrochloride

BCC6227 TC-E 5005

Products for Phosphodiesterases