Hot Natural Products & Bioactive Compounds
BioCrick offers high-purity natural products and bioactive compounds for scientific research. Our natural product collection includes compounds derived from plants, microorganisms and other biological sources and is widely used in pharmacological, biochemical and drug discovery research.
Natural products remain an important source of bioactive molecules and drug leads. BioCrick provides researchers with high-quality natural product compounds together with catalog numbers, product information and biological activity data.
Hot Products from BioCrick
Showing 873 - 880 of 9359 hot products
| Catalog No. | Product Name |
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| BCC4471 | Tyrphostin 9 |
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Potent uncoupler of oxidative phosphorylation.
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| BCC4483 | Ethynodiol diacetate |
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Ethynodiol diacetate is a steroidal progestin which is used as a hormonal contraceptive, it has relatively little or no potency as an androgen,has significant estrogenic effects.
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| BCC4486 | Mifepristone |
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Selective antagonist at progesterone (PR) and glucocorticoid (GR) receptors <em>in vitro</em> and <em>in vivo</em>. Is a silent antagonist at PR and has a higher affinity than progesterone. Has higher affinity for GR than dexamethasone.
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| BCC4488 | Raloxifene HCl |
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Selective estrogen receptor modulator (SERM) that binds to ER<span class='symbol'>α</span> and ER<span class='symbol'>β</span>, and tissue-dependently activates or blocks estrogen-induced transcription. Acts as an antiestrogen in breast and uterine tissue, but displays estrogen agonist activity in bone. In D12 rat hypothalamic cells, inhibits progesterone receptor induction by estrogen with an IC<sub>50</sub> of 1 nM.
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| BCC4496 | PF-573228 |
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Potent and selective inhibitor of focal adhesion kinase (FAK) (IC<sub>50</sub> = 4 nM). Displays 50 - 250-fold selectivity for FAK over other protein kinases. Blocks serum and fibronectin-directed migration and decreases focal adhesion turnover <em>in vitro</em>.
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| BCC4497 | Erastin |
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Antitumor agent; selective for cells expressing oncogenic RAS. Also Ferroptosis activator; induces oxidative, non-apoptotic cell death in tumors by modulating mitochondrial voltage-dependent anion channels (VDAC). Cell permeable.
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| BCC4500 | GW4064 |
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Selective, non-steroidal farnesoid X receptor (FXR) agonist (EC<sub>50</sub> = 15 nM). Displays no activity at other nuclear receptors at concentrations up to 1 <span class='symbol'>μ</span>M. Improves hyperglycaemia and hyperlipidemia in diabetic db/db mice. Shown to suppress autophagy in nutrient-deprived mouse hepatocytes.
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| BCC4503 | (R)-baclofen |
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More active enantiomer of (<em>RS</em>)-Baclofen, a selective GABA<sub>B</sub> agonist.
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