Hot Natural Products & Bioactive Compounds
BioCrick offers high-purity natural products and bioactive compounds for scientific research. Our natural product collection includes compounds derived from plants, microorganisms and other biological sources and is widely used in pharmacological, biochemical and drug discovery research.
Natural products remain an important source of bioactive molecules and drug leads. BioCrick provides researchers with high-quality natural product compounds together with catalog numbers, product information and biological activity data.
Hot Products from BioCrick
Showing 849 - 856 of 9359 hot products
| Catalog No. | Product Name |
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| BCC4392 | SB590885 |
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Potent B-Raf inhibitor (Kd = 0.3 nM). Selective for B-Raf against 46 other kinases (Ki app values are 0.16 and 1.72 nM for B-Raf and c-Raf respectively). Decreases anchorage-independent growth of melanoma cell lines. Inhibits ERK phosphorylation and proliferation in tumor cells expressing B-RafV600E.
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| BCC4395 | Benidipine HCl |
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Orally active antihypertensive agent which displays a wide range of activities <em>in vitro</em> and <em>in vivo</em>. Inhibits L-, N- and T-type Ca<sup>2+</sup> channels. Also inhibits aldosterone-induced mineralocorticoid receptor activation. Exhibits cardioprotective and antiartherosclerotic effects.
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| BCC4397 | Amlodipine Besylate |
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L-type calcium channel blocker that displays antihypertensive properties. Inhibits Ca<sup>2+</sup>-induced contractions in depolarized rat aorta (IC<sub>50</sub> = 1.9 nM) and displays vasoprotective effects in cardiovascular disease. Inhibits proliferation of human vascular smooth muscle cells and epidermoid carcinoma A431 cells (IC<sub>50</sub> = 25 <span class='symbol'>μ</span>M).
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| BCC4398 | Flunarizine 2HCl |
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Dual Na+/Ca2+ channel blocker; a cerebral and peripheral vasodilator. Neuroprotective.
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| BCC4402 | Felodipine |
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L-type Ca2+ channel blocker that is selective over N-, R-, P/Q- and T-type channels. Displays high vascular selectivity; lowers arterial blood pressure without altering cardiac contractility. Antihypertensive.
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| BCC4408 | Cinacalcet HCl |
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Calcium-sensing receptor (CaSR) allosteric agonist. Activates CaSR signaling in cellular proliferation and phosphatidylinositol (PI) hydrolysis assays. Reduces serum parathyroid hormone levels in rats. Also potent CYP2D2 inhibitor (IC50 = 87 nM) and L-type calcium channel blocker. Orally bioavailable.
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| BCC4410 | BML-190 |
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Potent and selective CB<sub>2</sub> receptor ligand (K<sub>i</sub> values are 435 nM and > 2 <span class='symbol'>μ</span>M for CB<sub>2</sub> and CB<sub>1</sub> respectively).
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| BCC4411 | Org 27569 |
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Potent CB1 receptor allosteric modulator (pEC50 = 8.24). Significantly increases binding of the CB1 agonist [3H]CP 55.940 (pKb = 5.67) and decreases binding of the CB1 inverse agonist [3H]SR 141716A (pKb = 5.95). Inhibits CB1 receptor antagonist efficacy in vitro (pKb = 7.57).
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