Hot Natural Products & Bioactive Compounds
BioCrick offers high-purity natural products and bioactive compounds for scientific research. Our natural product collection includes compounds derived from plants, microorganisms and other biological sources and is widely used in pharmacological, biochemical and drug discovery research.
Natural products remain an important source of bioactive molecules and drug leads. BioCrick provides researchers with high-quality natural product compounds together with catalog numbers, product information and biological activity data.
Hot Products from BioCrick
Showing 809 - 816 of 9359 hot products
| Catalog No. | Product Name |
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| BCC4293 | SB 203580 hydrochloride |
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Water-soluble salt of SB 203580. Selective inhibitor of p38 mitogen-activated protein kinase (IC<sub>50</sub> values are 50 and 500 nM for SAPK2a/p38 and SAPK2b/p38<span class='symbol'>β</span>2 respectively). Displays 100-500-fold selectivity over LCK, GSK3<span class='symbol'>β</span> and PKB<span class='symbol'>α</span>. Shown to inhibit interleukin-2-induced T cell proliferation, cyclooxygenase-1 and -2, and thromboxane synthase.
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| BCC4297 | Minoxidil |
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Antihypertensive. Antialopecia agent. Kir6 channel (KATP) activator.
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| BCC4302 | SR-3677 |
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Potent and selective Rho-kinase inhibitor (IC50 values are 3 and 56 nM for ROCK-II and ROCK-I respectively).
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| BCC4308 | A 419259 trihydrochloride |
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Potent Hck inhibitor (IC50 = 0.43 nM). Also inhibits other Src family kinases (SFKs). Suppresses proliferation and induces apoptosis in CML cell lines including CD34+. Also inhibits acute myeloid leukemia (AML) stem cell proliferation in vitro and in vivo.
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| BCC4316 | CGS 21680 HCl |
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A<sub>2A</sub> adenosine receptor agonist (K<sub>i</sub> = 27 nM). Has affinity for A<sub>1</sub> and A<sub>3</sub> adenosine receptors but can be used to distinguish A<sub>2A</sub>- and A<sub>2B</sub>-mediated effects.
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| BCC4324 | Carvedilol |
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Potent <span class='symbol'>β</span>-adrenoceptor and <span class='symbol'>α</span><sub>1</sub>-adrenoceptor antagonist (K<sub>i</sub> values are 0.81, 0.96 and 2.2 nM for <span class='symbol'>β</span><sub>1</sub>-, <span class='symbol'>β</span><sub>2</sub>- and <span class='symbol'>α</span><sub>1</sub>-adrenoceptors respectively) that displays antihypertensive and peripheral vasodilatory activity. Blocks cardiac inward-rectifier K<sup>+</sup> (K<sub>IR</sub>) channels, voltage-dependent Ca<sup>2+</sup> channels and exhibits antioxidant properties at higher concentrations.
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| BCC4325 | Clonidine HCl |
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Prototypical I<sub>1</sub> imidazoline receptor ligand. <span class='symbol'>α</span><sub>2</sub>-adrenergic receptor agonist. Antihypertensive. Also thought to enhance autophagy; shown to increase LC3-II levels in PC12 cells.
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| BCC4327 | Guanabenz Acetate |
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<span class='symbol'>α</span><sub>2</sub>-adrenergic agonist and IGRS (imidazoline I<sub>2</sub> binding site) selective ligand.
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