Hot Natural Products & Bioactive Compounds
BioCrick offers high-purity natural products and bioactive compounds for scientific research. Our natural product collection includes compounds derived from plants, microorganisms and other biological sources and is widely used in pharmacological, biochemical and drug discovery research.
Natural products remain an important source of bioactive molecules and drug leads. BioCrick provides researchers with high-quality natural product compounds together with catalog numbers, product information and biological activity data.
Hot Products from BioCrick
Showing 801 - 808 of 9359 hot products
| Catalog No. | Product Name |
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| BCC4251 | Haloperidol hydrochloride |
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Dopamine antagonist with selectivity for D2-like receptors (Ki values are 1.2, ~ 7, 2.3, ~ 80 and ~ 100 nM for D2, D3, D4, D1 and D5 receptors respectively). Subtype-selective NMDA antagonist.
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| BCC4253 | PYZD-4409 |
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Ubiquitin-activating enzyme (E1) inhibitor. Blocks degradation of p53 and cyclin D3. Inhibits NF-<span class='symbol'>κ</span>B activation and induces cell death associated with ER stress. Displays antitumor effects in a mouse model of leukemia.
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| BCC4258 | TDZD-8 |
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Selective non-ATP competitive inhibitor of GSK 3β (IC50 = 2 μM); thiadiazolidinone deriviative. Does not inhibit Cdk-1/cyclin B, CK-II, PKA or PKC at >100 μM. Reduces severity of L-dopa-induced dyskinesia in a Parkinson's disease in vivo model.
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| BCC4267 | (3S,4R)-Tofacitinib |
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(3S,4R)-Tofacitinib is an enantiomer of Tofacitinib. Tofacitinib inhibits JAK3 with IC50 of 1 nM.
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| BCC4268 | (3R,4S)-Tofacitinib |
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(3R,4S)-Tofacitinib is an enantiomer of Tofacitinib. Tofacitinib inhibits JAK3 with IC50 of 1 nM.
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| BCC4270 | Deltarasin hydrochloride |
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High affinity PDE<span class='symbol'>δ</span>-KRAS interaction inhibitor (K<sub>d</sub> = 41 nM); binds to PDE<span class='symbol'>δ</span>. Reduces proliferation and induces cell death of KRAS-dependent Panc-Tu-1 and Capan-1 pancreatic cancer cells. Attenuates tumor growth of Panc-Tu-1 xenografts in mice.
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| BCC4273 | LXR-623 |
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Potent LXR agonist (IC<sub>50</sub> values are 24 and 179 nM for LXR<span class='symbol'>β</span> and LXR<span class='symbol'>α</span>, respectively). Reduces total serum cholesterol and LDL cholesterol, and inhibits lesion growth in models of atherosclerosis. Increases ABCA1 and ABCG1 mRNA levels in rat peripheral blood cells. Orally bioavailable.
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| BCC4290 | A 839977 |
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Potent P2X7 antagonist; blocks BzATP-evoked calcium influx at recombinant human, rat and mouse P2X7 receptors (IC50 values are 20, 42 and 150 nM respectively). Displays antinociceptive effects in rat and mice models of inflammatory pain. CNS penetrant.
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