Hot Products
Hot products from BioCrick which is a professional high-purity natural products manufacturer are well known to scientists around the world because of their high purity and stability. Each product is a chemical compound or substance produced by a living organism—that is, found in nature. In the broadest sense, natural products include any substance produced by life.Natural products remain the best sources of drugs and drug leads, and this remains true today despite the fact that many pharmaceutical companies have deemphasized natural products research in favor of HTP screening of combinatorial libraries during the past 2 decades. From 1940s to date, 131 (74.8%) out of 175 small molecule anticancer drugs are natural product-based/inspired, with 85 (48.6%) being either natural products or derived therefrom. From 1981 to date, 79 (80%) out of 99 small molecule anticancer drugs are natural product-based/inspired, with 53 (53%) being either natural products or derived therefrom. Among the 20 approved small molecule New Chemical Entities (NCEs) in 2010, a half of them are natural products.
Hot products from the professional high-purity natural products manufacturer
| Cat.No. | Product Name |
|---|---|
| BCN2620 | Chenodeoxycholic acid |
| Chenodeoxycholic acid is a hydrophobic primary bile acid that activates nuclear receptors (FXR) involved in cholesterol metabolism. Chenodeoxycholic acid could reverse obesity in cHF-fed mice, mainly in response to the reduction in food intake. | |
| BCN2621 | Clinopodiside A |
| Clinopodiside A is a natural product from Clinopodium chinense. | |
| BCN2622 | Columbin |
| Columbin has anti-inflammation activity, it has chemopreventive ability against human colon cancer, it also can inhibit growth of culture forms of Trypanosoma brucei. Columbin inhibits PLA2 hydrolysis of ghost RBC in a dose-dependent fashion. | |
| BCN2623 | Cimicifugoside |
| 1. Cimicifugoside is a novel specific nucleoside transport inhibitor that displays synergistic potentiation of methotrexate cytotoxicity. 2. Cimicifugoside is a phytoestrogen, it can selectively inhibit nicotinic acetylcholine receptor (nAChR) -mediated response in bovine chromaffin cells. 3. Cimicifugoside shows immunosuppressive activity, which is preferentially directed toward B-cell function with larger doses being required for suppression of T-cell function. | |
| BCN2624 | Demethyl tetrandrine |
| Demethyl tetrandrine and tetrandrine show inhibition on DNA synthesis, the 50% inhibition doses ( ID50 ) are in L7712 and Sl80 cells are 27.5, 24.5 mg/L and 2.6, 3 .5mg/ L , respectively. | |
| BCN2625 | 4'-Demethylpodophyllotoxin |
| 4'-Demethylpodophyllotoxin exhibits the remarkable cytotoxic potential in diverse cancer cell lines. | |
| BCN2626 | Deoxynojirimycin hydrochloride |
| 1.1-Deoxynojirimycin hydrochloride shows inhibitory activity against α-glucosidases, inhibitors of α-glucosidase are promising candidates for the development of antitype II diabetics and anti-AIDS drugs. | |
| BCN2627 | alpha-Dihydroartemisinin |
| Dihydroartemisinin is widely used as an intermediate in the preparation of other artemisinin-derived antimalarial drugs, is recommended as the first-line anti-malarial drug with low toxicity. Dihydroartemisinin possesses promising anticancer activities and induce cancer cell death through apoptotic pathways. | |
