Hot Natural Products & Bioactive Compounds
BioCrick offers high-purity natural products and bioactive compounds for scientific research. Our natural product collection includes compounds derived from plants, microorganisms and other biological sources and is widely used in pharmacological, biochemical and drug discovery research.
Natural products remain an important source of bioactive molecules and drug leads. BioCrick provides researchers with high-quality natural product compounds together with catalog numbers, product information and biological activity data.
Hot Products from BioCrick
Showing 889 - 896 of 9359 hot products
| Catalog No. | Product Name |
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| BCC4531 | Ketotifen Fumarate |
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An H1 receptor antagonist.
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| BCC4533 | Ranitidine Hydrochloride |
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Potent, selective and competitive histamine H2 receptor antagonist (pA2 = 6.95 - 7.2). Inhibits gastric acid secretion induced by histamine, pentagastrin, bethanecol and food in vivo. Also inhibits aspirin-induced gastric lesions.
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| BCC4540 | Desloratadine |
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High affinity histamine H<sub>1</sub> receptor antagonist (K<sub>i</sub> = 0.87 nM); active metabolite of loratadine. Anti-inflammatory.
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| BCC4541 | Latrepirdine |
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Non-selective antihistamine that displays cognitive enhancing abilities. Also displays high affinity for 5-HT (particularly 5-HT<sub>6</sub> and 5-HT<sub>7</sub>), <span class='symbol'>α</span>-adrenergic, dopaminergic, AMPA and NMDA receptors, and L-type calcium channels. Does not inhibit acetylcholinesterase activity. Exhibits neuroprotective activity in cellular models of Alzheimer's and Huntington's disease and preserves cognitive function following administration to AF64A lesioned rats. Protects neurons against the neurotoxic action of <span class='symbol'>β</span>-amyloid fragment; shown to enhance autophagy in yeast and reduce intracellular A<span class='symbol'>β</span>42 levels.
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| BCC4542 | Fexofenadine HCl |
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Selective histamine H<sub>1</sub> receptor antagonist (pK<sub>i</sub> = 8.1). Active metabolite of terfenadine that displays non-sedating antiallergic effects.
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| BCC4543 | JNJ-7777120 |
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Histamine H4 receptor antagonist; displays high affinity (Ki = 4.5 nM) and is >1000-fold selective for H4 over other histamine receptors.
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| BCC4545 | Olopatadine HCl |
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Histamine H1 receptor antagonist (Ki = 31.6 nM). Inhibits the release of histamine, prostaglandin D2 and tryptase in a concentration-dependent manner. Mast cell stabilizer; inhibits mast cell mediator release. Also suppresses inflammation by inhibition of cytokine production.
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| BCC4546 | C646 |
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Selective p300/CREB-binding protein (CBP) inhibitor (Ki = 400 nM). Selective for p300 over six other histone acetyltransferases (HATs). Suppresses histone H3 and H4 acetylation in mouse fibroblast cell lines.
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