Hot Products
Hot products from BioCrick which is a professional high-purity natural products manufacturer are well known to scientists around the world because of their high purity and stability. Each product is a chemical compound or substance produced by a living organism—that is, found in nature. In the broadest sense, natural products include any substance produced by life.Natural products remain the best sources of drugs and drug leads, and this remains true today despite the fact that many pharmaceutical companies have deemphasized natural products research in favor of HTP screening of combinatorial libraries during the past 2 decades. From 1940s to date, 131 (74.8%) out of 175 small molecule anticancer drugs are natural product-based/inspired, with 85 (48.6%) being either natural products or derived therefrom. From 1981 to date, 79 (80%) out of 99 small molecule anticancer drugs are natural product-based/inspired, with 53 (53%) being either natural products or derived therefrom. Among the 20 approved small molecule New Chemical Entities (NCEs) in 2010, a half of them are natural products.
Hot products from the professional high-purity natural products manufacturer
| Cat.No. | Product Name |
|---|---|
| BCN2646 | Noroxyhydrastinine |
| Noroxyhydrastinine exhibits potent melanogenesis-inhibitory activities, it inhibits melanogenesis, at least in part, by inhibiting the expression of protein levels of tyrosinase, TRP-1, and TRP-2 in α-MSH-stimulated B16 melanoma cells. | |
| BCN2647 | Palmatrubine |
| Palmatrubine binds to double-stranded DNA most probably via an intercalating mode. | |
| BCN2648 | Tetrahydroberberine |
| Tetrahydroberberine, with D(2) receptor antagonist and 5-HT(1A) receptor agonist properties, has significant potential as a therapeutic for treatment of FD; it has antidopaminergic effect, and other pharmacological action on the central nervous system. Tetrahydroberberine can inhibit the rabbit platelet aggregation. | |
| BCN2649 | Tetrahydroepiberberine |
| Tetrahydroepiberberine is a natural product from Sinomenium acutum. | |
| BCN2650 | Oxoglaucine |
| Oxoglaucine exerts immunomodulatory effect in vivo in a dose-dependent and protocol-dependent manner, it also exhibits significant antiplatelet aggregation activity against rabbit platelets induced by thrombin, arachidonic acid, collagen or platelet activating factor. Oxoglaucine and pachypodol are anti-picornavirus compounds, phosphatidylinositol 4-kinase III beta (PI4KB) as the direct target of them. | |
| BCN2651 | Berberrubine |
| Berberrubine possesses diverse pharmacological activities, including glucose-lowering, lipid-lowering, anti-inflammatory, and anti-tumor effects. Berberrubine dose-dependently inhibits IL-8 and MCP-1 protein levels in the media and mRNA expression of the cells stimulated with IL-1beta or TNF-alpha. | |
| BCN2652 | Columbianetin acetate |
| Columbianetin may be helpful in regulating mast cell-mediated allergic inflammatory responses, the absorption of columbianetin acetate is a passive diffusion process without pH-dependent. | |
| BCN2653 | Phillygenin |
| Phillyrin, (+)-Phillygenin, and (-)-phillygenin exert the strongest inhibitory activities on NO production with IC(50) values. | |
