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Brassicasterol

CAS# 474-67-9

Brassicasterol

Catalog No. BCN2613----Order now to get a substantial discount!

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Quality Control of Brassicasterol

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Chemical structure

Brassicasterol

3D structure

Chemical Properties of Brassicasterol

Cas No. 474-67-9 SDF Download SDF
PubChem ID 5281327 Appearance Cryst.
Formula C28H46O M.Wt 398.66
Type of Compound Steroids Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name (3S,8S,9S,10R,13R,14S,17R)-17-[(E,2R,5R)-5,6-dimethylhept-3-en-2-yl]-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol
SMILES CC(C)C(C)C=CC(C)C1CCC2C1(CCC3C2CC=C4C3(CCC(C4)O)C)C
Standard InChIKey OILXMJHPFNGGTO-ZAUYPBDWSA-N
Standard InChI InChI=1S/C28H46O/c1-18(2)19(3)7-8-20(4)24-11-12-25-23-10-9-21-17-22(29)13-15-27(21,5)26(23)14-16-28(24,25)6/h7-9,18-20,22-26,29H,10-17H2,1-6H3/b8-7+/t19-,20+,22-,23-,24+,25-,26-,27-,28+/m0/s1
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Brassicasterol

The seeds of Brassica campestris L.

Biological Activity of Brassicasterol

Description1. Brassicasterol may be a relevant additional biomarker in Alzheimer's disease (AD).

Brassicasterol Dilution Calculator

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Brassicasterol Molarity Calculator

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Preparing Stock Solutions of Brassicasterol

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.5084 mL 12.542 mL 25.084 mL 50.1681 mL 62.7101 mL
5 mM 0.5017 mL 2.5084 mL 5.0168 mL 10.0336 mL 12.542 mL
10 mM 0.2508 mL 1.2542 mL 2.5084 mL 5.0168 mL 6.271 mL
50 mM 0.0502 mL 0.2508 mL 0.5017 mL 1.0034 mL 1.2542 mL
100 mM 0.0251 mL 0.1254 mL 0.2508 mL 0.5017 mL 0.6271 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on Brassicasterol

Sterol lipid metabolism in down syndrome revisited: down syndrome is associated with a selective reduction in serum brassicasterol levels.[Pubmed:22649448]

Curr Gerontol Geriatr Res. 2012;2012:179318.

Over the past 15 years, insights into sterol metabolism have improved our understanding of the relationship between lipids and common conditions such as atherosclerosis and Alzheimer's Disease (AD). A better understanding of sterol lipid metabolism in individuals with Down Syndrome (DS) may help elucidate how this population's unique metabolic characteristics influence their risks for atherosclerosis and AD. To revisit the question of whether sterol lipid parameters may be altered in DS subjects, we performed a pilot study to assess traditional serum sterol lipids and lipoproteins, as well as markers of sterol biosynthesis, metabolites, and plant sterols in 20 subjects with DS compared to age-matched controls. Here we report that the levels of nearly all lipids and lipoproteins examined are similar to control subjects, suggesting that trisomy 21 does not lead to pronounced general alterations in sterol lipid metabolism. However, the levels of serum Brassicasterol were markedly reduced in DS subjects.

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