Chrysocauloflavone ICAS# 899789-51-6 |
Quality Control & MSDS
Number of papers citing our products
![](/media/diy/images/number_cite.png)
Chemical structure
![Chrysocauloflavone I](/media/images/struct/BCN0705.png)
Cas No. | 899789-51-6 | SDF | Download SDF |
PubChem ID | N/A | Appearance | Yellow powder |
Formula | C30H20O10 | M.Wt | 540.5 |
Type of Compound | Flavonoids | Storage | Desiccate at -20°C |
Solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | ||
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
||
About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
||
Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. |
![](/statics/images/closeICO.png)
Chrysocauloflavone I Dilution Calculator
![](/statics/images/closeICO.png)
Chrysocauloflavone I Molarity Calculator
1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
1 mM | 1.8501 mL | 9.2507 mL | 18.5014 mL | 37.0028 mL | 46.2535 mL |
5 mM | 0.37 mL | 1.8501 mL | 3.7003 mL | 7.4006 mL | 9.2507 mL |
10 mM | 0.185 mL | 0.9251 mL | 1.8501 mL | 3.7003 mL | 4.6253 mL |
50 mM | 0.037 mL | 0.185 mL | 0.37 mL | 0.7401 mL | 0.9251 mL |
100 mM | 0.0185 mL | 0.0925 mL | 0.185 mL | 0.37 mL | 0.4625 mL |
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. |
![](/media/diy/images/pphome/Calcutta University.jpg)
Calcutta University
![](/media/diy/images/pphome/University of Minnesota.jpg)
University of Minnesota
![](/media/diy/images/pphome/University of Maryland School of Medicine.jpg)
University of Maryland School of Medicine
![](/media/diy/images/pphome/University of Illinois at Chicago.jpg)
University of Illinois at Chicago
![](/media/diy/images/pphome/The Ohio State University.jpg)
The Ohio State University
![](/media/diy/images/pphome/University of Zurich.jpg)
University of Zurich
![](/media/diy/images/pphome/Harvard University.jpg)
Harvard University
![](/media/diy/images/pphome/Colorado State University.jpg)
Colorado State University
![](/media/diy/images/pphome/Auburn University.jpg)
Auburn University
![](/media/diy/images/pphome/Yale University.jpg)
Yale University
![](/media/diy/images/pphome/Worcester Polytechnic Institute.jpg)
Worcester Polytechnic Institute
![](/media/diy/images/pphome/Washington State University.jpg)
Washington State University
![](/media/diy/images/pphome/Stanford University.jpg)
Stanford University
![](/media/diy/images/pphome/University of Leipzig.jpg)
University of Leipzig
![](/media/diy/images/pphome/Universidade da Beira Interior.jpg)
Universidade da Beira Interior
![](/media/diy/images/pphome/The Institute of Cancer Research.jpg)
The Institute of Cancer Research
![](/media/diy/images/pphome/Heidelberg University.jpg)
Heidelberg University
![](/media/diy/images/pphome/University of Amsterdam.jpg)
University of Amsterdam
![](/media/diy/images/pphome/University of Auckland.jpg)
University of Auckland
![TsingHua University](/media/diy/images/pphome/TsingHua University.jpg)
TsingHua University
![The University of Michigan](/media/diy/images/pphome/University of Michigan.jpg)
The University of Michigan
![Miami University](/media/diy/images/pphome/Miami University.jpg)
Miami University
![DRURY University](/media/diy/images/pphome/DRURY University.jpg)
DRURY University
![Jilin University](/media/diy/images/pphome/Jilin University.jpg)
Jilin University
![Fudan University](/media/diy/images/pphome/Fudan University.jpg)
Fudan University
![Wuhan University](/media/diy/images/pphome/Wuhan University.jpg)
Wuhan University
![Sun Yat-sen University](/media/diy/images/pphome/Sun Yat-sen University.jpg)
Sun Yat-sen University
![Universite de Paris](/media/diy/images/pphome/Universite de Paris.jpg)
Universite de Paris
![Deemed University](/media/diy/images/pphome/Deemed University.jpg)
Deemed University
![Auckland University](/media/diy/images/pphome/Auckland University.jpg)
Auckland University
![The University of Tokyo](/media/diy/images/pphome/Tokyo University.jpg)
The University of Tokyo
![Korea University](/media/diy/images/pphome/Korea University.jpg)
Korea University
- 3',3'''-Biapigenin
Catalog No.:BCN0704
CAS No.:151455-26-4
- Ochnaflavone
Catalog No.:BCN0703
CAS No.:50276-96-5
- Shanciol B
Catalog No.:BCN0702
CAS No.:208106-53-0
- 5,6-Dihydroxy-7,8-dimethoxyflavone
Catalog No.:BCN0701
CAS No.:76844-65-0
- Delicaflavone
Catalog No.:BCN0700
CAS No.:343569-15-3
- Luteolin 5-methyl ether
Catalog No.:BCN0699
CAS No.:58115-29-0
- Violanone
Catalog No.:BCN0698
CAS No.:52250-38-1
- Luteolin 5,3'-dimethyl ether
Catalog No.:BCN0697
CAS No.:62346-14-9
- (2S)-Pinocembrin 7-O-[2''-O-(5'''-O-trans-cinnamoyl)-β-D-apiofuranosyl]-β-D-glucoside
Catalog No.:BCN0696
CAS No.:773899-29-9
- Kayaflavone
Catalog No.:BCN0695
CAS No.:481-45-8
- E,Z-Platanoside
Catalog No.:BCN0694
CAS No.:1197343-17-1
- Quercetin 4'-O-galactoside
Catalog No.:BCN0693
CAS No.:381728-34-3
- 6,7,4'-Trihydroxyflavanone
Catalog No.:BCN0706
CAS No.:189689-31-4
- Procyanidin B2 3,3'-di-O-gallate
Catalog No.:BCN0707
CAS No.:79907-44-1
- 2'',3''-Dihydro-3',3'''-biapigenin
Catalog No.:BCN0708
CAS No.:151455-25-3
- 3',3'''-Binaringenin
Catalog No.:BCN0709
CAS No.:145399-99-1
- 2'',3''-Dihydroochnaflavone
Catalog No.:BCN0710
CAS No.:340997-02-6
- Procyanidin B5
Catalog No.:BCN0711
CAS No.:12798-57-1
- Procyanidin B2 3''-O-gallate
Catalog No.:BCN0712
CAS No.:73086-04-1
- 2"-O-Glucosylrutin
Catalog No.:BCN0713
CAS No.:55696-55-4
- 2,3-Dihydroamentoflavone
Catalog No.:BCN0714
CAS No.:34340-51-7
- Procyanidin B-5 3,3'-di-O-gallate
Catalog No.:BCN0715
CAS No.:106533-60-2
- Quercetin dimer
Catalog No.:BCN0716
CAS No.:167276-19-9
- 3'',4''-Di-O-p-coumaroylquercitrin
Catalog No.:BCN0717
CAS No.:437615-43-5
Pharmacokinetics, Tissue Distribution and Protein Binding Studies of Chrysocauloflavone I in Rats.[Pubmed:26576031]
Planta Med. 2016 Feb;82(3):217-23.
Chrysocauloflavone I, an unfrequent biflavonoid, was purified from Selaginella doederleinii in this study. It showed cytotoxic effects on three human cancer cells, NCI-H1975, A549, and HepG-2, in vitro. In silico assessment of the physicochemical properties was performed for predicting the permeability and intestinal absorption of the tested compound. Subsequently, a rapid, sensitive, and specific high-performance liquid chromatography method was developed for determination of the compound in different biological samples to ascertain the pharmacokinetics, tissue distribution, and protein binding profiles of this active ingredient in rats. After intravenous dosing of Chrysocauloflavone I at different levels (10 and 20 mg/kg), the elimination half-life was approximately 85 min, and the AUC0-infinity increased with the dose from 148.52 mg/L x min for 10 mg/kg to 399.01 mg/L x min for 20 mg/kg. After single intravenous dosing (20 mg/kg), Chrysocauloflavone I was detected in all tissues studied with higher levels in the heart, blood, and lungs. The results of equilibrium dialysis indicated a very high protein binding degree (over 97%) for Chrysocauloflavone I. After intragastric administration of 100 mg/kg Chrysocauloflavone I to rats, no parent drug was detected in the rat plasma. This is the first report of the favorable bioactivities, plasma pharmacokinetics, tissue distribution, and protein binding profiles of the rare biflavone Chrysocauloflavone I.