DigitoluteinCAS# 477-86-1 |
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| Cas No. | 477-86-1 | SDF | Download SDF |
| PubChem ID | 160475 | Appearance | Powder |
| Formula | C16H12O4 | M.Wt | 268.3 |
| Type of Compound | Anthraquinones | Storage | Desiccate at -20°C |
| Solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | ||
| Chemical Name | 2-hydroxy-1-methoxy-3-methylanthracene-9,10-dione | ||
| SMILES | CC1=C(C(=C2C(=C1)C(=O)C3=CC=CC=C3C2=O)OC)O | ||
| Standard InChIKey | WCRMDMYSQWZTSF-UHFFFAOYSA-N | ||
| Standard InChI | InChI=1S/C16H12O4/c1-8-7-11-12(16(20-2)13(8)17)15(19)10-6-4-3-5-9(10)14(11)18/h3-7,17H,1-2H3 | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
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| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
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| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
| Description | 1. Digitolutein, extracted from the stem bark and the roots of Morinda lucida Benth., has inhibition on the growth of Plasmodium falciparum in vitro. |
| Targets | Antifection |
Digitolutein Dilution Calculator
Digitolutein Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 3.7272 mL | 18.6359 mL | 37.2717 mL | 74.5434 mL | 93.1793 mL |
| 5 mM | 0.7454 mL | 3.7272 mL | 7.4543 mL | 14.9087 mL | 18.6359 mL |
| 10 mM | 0.3727 mL | 1.8636 mL | 3.7272 mL | 7.4543 mL | 9.3179 mL |
| 50 mM | 0.0745 mL | 0.3727 mL | 0.7454 mL | 1.4909 mL | 1.8636 mL |
| 100 mM | 0.0373 mL | 0.1864 mL | 0.3727 mL | 0.7454 mL | 0.9318 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
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Effects of three compounds extracted from Morinda lucida on Plasmodium falciparum.[Pubmed:1484892]
Planta Med. 1992 Dec;58(6):533-4.
The effects of three compounds, Digitolutein (1), rubiadin 1-methyl ether (2) and damnacanthal (3) extracted from the stem bark and the roots of Morinda lucida Benth. on the growth of Plasmodium falciparum in vitro were investigated. The number of parasites (schizonts) decreased significantly in a dose-dependent manner, and 100% of inhibition was obtained with 30 to 40 micrograms of each compound tested. The IC50 values were calculated.
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