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Emetine Hydrochloride

CAS# 14198-59-5

Emetine Hydrochloride

Catalog No. BCN2478----Order now to get a substantial discount!

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Quality Control of Emetine Hydrochloride

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Chemical structure

Emetine Hydrochloride

3D structure

Chemical Properties of Emetine Hydrochloride

Cas No. 14198-59-5 SDF Download SDF
PubChem ID 6603320 Appearance Powder
Formula C29H41ClN2O4 M.Wt 517.1
Type of Compound Alkaloids Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name (2S,3R,11bS)-2-[[(1R)-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinolin-1-yl]methyl]-3-ethyl-9,10-dimethoxy-2,3,4,6,7,11b-hexahydro-1H-benzo[a]quinolizine;hydrochloride
SMILES CCC1CN2CCC3=CC(=C(C=C3C2CC1CC4C5=CC(=C(C=C5CCN4)OC)OC)OC)OC.Cl
Standard InChIKey HUEYSSLYFJVUIS-MRFSYGAJSA-N
Standard InChI InChI=1S/C29H40N2O4.ClH/c1-6-18-17-31-10-8-20-14-27(33-3)29(35-5)16-23(20)25(31)12-21(18)11-24-22-15-28(34-4)26(32-2)13-19(22)7-9-30-24;/h13-16,18,21,24-25,30H,6-12,17H2,1-5H3;1H/t18-,21-,24+,25-;/m0./s1
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Emetine Hydrochloride

The roots of Alangium chinense (Lour.) Harms

Biological Activity of Emetine Hydrochloride

Description1. Emetine hydrochloride and dehydroemetine combined with chloroquine in the treatment of children with amoebic liver abscess.

Emetine Hydrochloride Dilution Calculator

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Emetine Hydrochloride Molarity Calculator

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Preparing Stock Solutions of Emetine Hydrochloride

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 1.9339 mL 9.6693 mL 19.3386 mL 38.6772 mL 48.3465 mL
5 mM 0.3868 mL 1.9339 mL 3.8677 mL 7.7354 mL 9.6693 mL
10 mM 0.1934 mL 0.9669 mL 1.9339 mL 3.8677 mL 4.8347 mL
50 mM 0.0387 mL 0.1934 mL 0.3868 mL 0.7735 mL 0.9669 mL
100 mM 0.0193 mL 0.0967 mL 0.1934 mL 0.3868 mL 0.4835 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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Description

Emetine hydrochloride, derived from the ipecac root, is a potent anti-protozoal and emetic agent. Emetine hydrochloride inhibits viral polymerases and inhibits Zika and Ebola virus infections. Emetine hydrochloride potently inhibits autophagy and has anti-malarial, anti-bacterial and anti-amoebic effect.

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