Lysicamine

CAS# 15444-20-9

Lysicamine

Catalog No. BCN6523----Order now to get a substantial discount!

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Lysicamine: 5mg Please Inquire In Stock
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Quality Control of Lysicamine

Number of papers citing our products

Chemical structure

Lysicamine

3D structure

Chemical Properties of Lysicamine

Cas No. 15444-20-9 SDF Download SDF
PubChem ID 122691 Appearance Powder
Formula C18H13NO3 M.Wt 291.3
Type of Compound Alkaloids Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
SMILES COC1=C(C2=C3C(=C1)C=CN=C3C(=O)C4=CC=CC=C42)OC
Standard InChIKey DPBMWJXWUINLQT-UHFFFAOYSA-N
Standard InChI InChI=1S/C18H13NO3/c1-21-13-9-10-7-8-19-16-14(10)15(18(13)22-2)11-5-3-4-6-12(11)17(16)20/h3-9H,1-2H3
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Lysicamine

The barks of Magnolia officinalis

Biological Activity of Lysicamine

Description1. Lysicamine has antimicrobial and anti-inflammation activity, the minimum inhibitory concentrations of the pour component (Streptococcus mutans, Porphyromonas gingivalis, Actinobacillus actinomycetemcomitans and Candida albicans.) is less than 5mg/ml for all four microorganisms and the minimum concentration with anti-inflammation is 0.2mg/ml for both IL-8 and IL-6. 2. Lysicamine has antileishmanial activity. 3. Lysicamine shows significant antioxidant capacity in the ORAC(FL) assay and it is active against S. epidermidis and C. dubliniensis, with MIC values in the range 12.5-100 microg mL(-1). 4. Lysicamine can significantly inhibit the proliferation of melanoma cells, it has antioxidative activity and chemopreventive activity in skin melanoma cells.
TargetsIL Receptor | Antifection

Lysicamine Dilution Calculator

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Lysicamine Molarity Calculator

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Preparing Stock Solutions of Lysicamine

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 3.4329 mL 17.1644 mL 34.3289 mL 68.6577 mL 85.8222 mL
5 mM 0.6866 mL 3.4329 mL 6.8658 mL 13.7315 mL 17.1644 mL
10 mM 0.3433 mL 1.7164 mL 3.4329 mL 6.8658 mL 8.5822 mL
50 mM 0.0687 mL 0.3433 mL 0.6866 mL 1.3732 mL 1.7164 mL
100 mM 0.0343 mL 0.1716 mL 0.3433 mL 0.6866 mL 0.8582 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on Lysicamine

Antioxidant and anticancer constituents from the leaves of Liriodendron tulipifera.[Pubmed:24705566]

Molecules. 2014 Apr 3;19(4):4234-45.

Sixteen compounds were extracted and purified from the leaves of Liriodendron tulipifera. These compounds include aporphines, oxoaporphine, coumarin, sesquiterpene lactone, benzenoids, cyclitol and steroids. (+)-Norstephalagine (2) (an aporphine) and scopoletin (8) (a coumarin) were isolated from Liriodendron tulipifera leaves from the first time. The identified compounds were screened for their antiradical scavenging, metal chelating and ferric reducing power activities. The results have showed that these compounds have antioxidative activity. The study has also examined the chemopreventive property of the isolated compounds against human melanoma cells A375. The results shown that (-)-anonaine (1), (-)-liridinine (3), (+)-lirinidine (6), Lysicamine (7) and epitulipinolide diepoxide (9) significantly inhibited the proliferation of melanoma cells. These results revealed that these compounds have antioxidative activity and chemopreventive activity in skin melanoma cells.

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