Epilepsy Research

Epilepsy is a group of neurological conditions consisting of recurrent, usually unprovoked epileptic seizures. Epileptic seizures have recently been defined as "a transient occurrence of signs and/or symptoms due to abnormal, excessive or synchronous neuronal activity in the brain". Epilepsy is one of the most common disorders of the brain, with one in 10 people suffering at least one seizure in their lifetime. There are over 40 different types of epilepsy, each of which presents with its own unique combination of seizure type, typical age of onset, EEG findings, treatment, and prognosis.

Epilepsy Research Products Targets

Products for Epilepsy Research - Page 27

  1. Cat.No. Product Name Information/Activity
  2. BCC6013 GLYX 13 Rapastinel (GLYX-13) is an N-methyl-D-aspartate receptor (NMDAR) modulator that has characteristics of a glycine site partial agonist. GLYX 13 chemical structure
  3. BCC6588 (R)-(+)-HA-966 (R)-(+)-HA-966 ((+)-HA-966) is a partial agonist/antagonist of glycine site of the N-methyl-D-aspartate (NMDA) receptor complex. (R)-(+)-HA-966 selectively blocks the activation of the mesolimbic dopamine system by amphetamine. (R)-(+)-HA-966 can cross the blood-brain barrier and has the potential for neuropathic and acute pain. (R)-(+)-HA-966 chemical structure
  4. BCC6570 Homoquinolinic acid 490-75-5 Homoquinolinic acid chemical structure
  5. BCC6591 Ibotenic acid Ibotenic acid has agonist activity at both the N-methyl-D-aspartate (NMDA) and trans-ACPD or metabolotropic quisqualate (Qm) receptor sites. Ibotenic acid chemical structure
  6. BCC5896 MNI-caged-D-aspartate 845555-94-4 MNI-caged-D-aspartate chemical structure
  7. BCC4590 NMDA (N-Methyl-D-aspartic acid) NMDA is a specific agonist for NMDA receptor mimicking the action of glutamate, the neurotransmitter which normally acts at that receptor. NMDA (N-Methyl-D-aspartic acid) chemical structure
  8. BCC6573 Quinolinic acid Quinolinic acid is an endogenous N-methyl-D-aspartate (NMDA) receptor agonist synthesized from L-tryptophan via the kynurenine pathway and thereby has the potential of mediating N-methyl-D-aspartate neuronal damage and dysfunction. Quinolinic acid chemical structure
  9. BCC6865 Spermidine trihydrochloride Spermidine trihydrochloride maintains cell membrane stability, increases antioxidant enzymes activities, improving photosystem II (PSII), and relevant gene expression. Spermidine trihydrochloride significantly decreases the H2O2 and O2.- contents. Spermidine trihydrochloride chemical structure
  10. BCC6599 (RS)-(Tetrazol-5-yl)glycine (RS)-(Tetrazol-5-yl)glycine (D,L-(tetrazol-5-yl)glycine) is a highly potent and selective N-methyl-D-aspartate (NMDA) receptor agonist. (RS)-(Tetrazol-5-yl)glycine has EC50s of 99 nM, 1.7 μM for GluN1/GluN2D and GluN1/GluN2A, respectively. (RS)-(Tetrazol-5-yl)glycine induces seizure responses and Fos in mice. (RS)-(Tetrazol-5-yl)glycine chemical structure
  11. BCC6584 ACBC 22264-50-2 ACBC chemical structure

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