Epilepsy Research

Epilepsy is a group of neurological conditions consisting of recurrent, usually unprovoked epileptic seizures. Epileptic seizures have recently been defined as "a transient occurrence of signs and/or symptoms due to abnormal, excessive or synchronous neuronal activity in the brain". Epilepsy is one of the most common disorders of the brain, with one in 10 people suffering at least one seizure in their lifetime. There are over 40 different types of epilepsy, each of which presents with its own unique combination of seizure type, typical age of onset, EEG findings, treatment, and prognosis.

Epilepsy Research Products Targets

Products for Epilepsy Research - Page 5

  1. Cat.No. Product Name Information/Activity
  2. BCC3745 Carbenoxolone disodium 7421-40-1 Carbenoxolone disodium chemical structure
  3. BCC1032 Gap 26 Gap 26 is a connexin mimetic peptide corresponding to the residues 63-75 of connexin 43, which is a gap junction blocker. Gap 26 chemical structure
  4. BCC1033 Gap 27 Gap 27, connexin43 mimetic peptide, is a gap junction inhibitor. Gap 27 chemical structure
  5. BCC5599 Gap19 Gap19, a peptide derived from nine amino acids of the Cx43 cytoplasmic loop (CL), is a potent and selective connexin 43 (Cx43) hemichannel blocker. Gap19 inhibits hemichannels caused by preventing intramolecular interactions of the C-terminus (CT) with the CL. Gap19 is not blocking GJ channels or Cx40/pannexin-1 hemichannels. Gap19 has protective effects against myocardial. Gap19 chemical structure
  6. BCC5033 Amitriptyline HCl Amitriptyline hydrochloride is a dibenzocycloheptene-derivative tricyclic antidepressant (TCA). Amitriptyline HCl chemical structure
  7. BCC5944 BDNF (human) 218441-99-7 BDNF (human) chemical structure
  8. BCC6072 7,8-Dihydroxyflavone 7,8-Dihydroxyflavone is a potent and selective TrkB agonist that mimics the physiological actions of Brain-derived neurotrophic factor (BDNF). Displays therapeutic efficacy toward various neurological diseases. 7,8-Dihydroxyflavone chemical structure
  9. BCC6239 LM 22A4 LM22A-4 is a specific agonist of tyrosine kinase receptor B, used for neurological disease research. LM 22A4 chemical structure
  10. BCC6287 ANA 12 ANA-12 is a potent and selective TrkB antagonist with IC50s of 45.6 nM and 41.1 μM for the high and low affinity sites, respectively. ANA 12 chemical structure
  11. BCC6357 Cyclotraxin B 1203586-72-4 Cyclotraxin B chemical structure

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