Epilepsy Research
Epilepsy is a group of neurological conditions consisting of recurrent, usually unprovoked epileptic seizures. Epileptic seizures have recently been defined as "a transient occurrence of signs and/or symptoms due to abnormal, excessive or synchronous neuronal activity in the brain". Epilepsy is one of the most common disorders of the brain, with one in 10 people suffering at least one seizure in their lifetime. There are over 40 different types of epilepsy, each of which presents with its own unique combination of seizure type, typical age of onset, EEG findings, treatment, and prognosis.
Epilepsy Research Products Targets
- NHE (3)
- Monocarboxylate Transporter (3)
- VEGFR (16)
- FGFR (5)
- Voltage-gated Sodium (NaV) Channel (30)
- Voltage-gated Potassium (KV) Channel (38)
- Voltage-gated Calcium Channel (CaV) (38)
- Others (13)
- Epithelial Sodium Channel (3)
- STIM-Orai Channel (4)
- Ryanodine Receptor (6)
- Glutamate (Metabotropic) Group III Receptor (26)
- Glutamate (Metabotropic) Group II Receptor (33)
- Glutamate (Metabotropic) Group I Receptor (54)
- AMPA Receptor (45)
- GABAA-ρ Receptor (8)
- GABAA Receptor (66)
- NMDA Receptor (87)
- Kainate Receptor (22)
- IP3 Receptor (2)
- Gap Channel (7)
- Trk Receptor (13)
- Acid-Sensing Ion Channel (3)
- Calcium-Activated Potassium (KCa) Channel (19)
- Inward Rectifier Potassium (Kir) Channel (21)
- Sodium and Potassium ATPase (3)
- KCC2 (1)
- H+-ATPase (3)
- H+,K+-ATPase (4)
- Chloride Channel (17)
- NCX (5)
- Ca2+-ATPase (7)
- NKCC (2)
- Cytokine (15)
Products for Epilepsy Research - Page 5
- Cat.No. Product Name Information/Activity
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BCC3745
Carbenoxolone disodium
7421-40-1
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BCC1032
Gap 26
Gap 26 is a connexin mimetic peptide corresponding to the residues 63-75 of connexin 43, which is a gap junction blocker.
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BCC1033
Gap 27
Gap 27, connexin43 mimetic peptide, is a gap junction inhibitor.
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BCC5599
Gap19
Gap19, a peptide derived from nine amino acids of the Cx43 cytoplasmic loop (CL), is a potent and selective connexin 43 (Cx43) hemichannel blocker. Gap19 inhibits hemichannels caused by preventing intramolecular interactions of the C-terminus (CT) with the CL. Gap19 is not blocking GJ channels or Cx40/pannexin-1 hemichannels. Gap19 has protective effects against myocardial.
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BCC5033
Amitriptyline HCl
Amitriptyline hydrochloride is a dibenzocycloheptene-derivative tricyclic antidepressant (TCA).
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BCC5944
BDNF (human)
218441-99-7
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BCC6072
7,8-Dihydroxyflavone
7,8-Dihydroxyflavone is a potent and selective TrkB agonist that mimics the physiological actions of Brain-derived neurotrophic factor (BDNF). Displays therapeutic efficacy toward various neurological diseases.
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BCC6239
LM 22A4
LM22A-4 is a specific agonist of tyrosine kinase receptor B, used for neurological disease research.
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BCC6287
ANA 12
ANA-12 is a potent and selective TrkB antagonist with IC50s of 45.6 nM and 41.1 μM for the high and low affinity sites, respectively.
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BCC6357
Cyclotraxin B
1203586-72-4


